STING agonist compound 3
Modify Date: 2026-08-02 15:38:24
STING agonist compound 3 structure
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Common Name | STING agonist compound 3 | ||
|---|---|---|---|---|
| CAS Number | 2138299-33-7 | Molecular Weight | 849.94 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C42H51N13O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of STING agonist compound 3diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist. |
| Name | diABZI STING agonist-1 |
|---|
| Description | diABZI STING agonist-1 is a selective stimulator of interferon genes (STING) receptor agonist. |
|---|---|
| Related Catalog | |
| Target |
STING[1]. |
| In Vivo | diABZI STING agonist-1 activates secretion of IFNβ, IL-6, TNF, and KC/GROα (also known as CXCL1) in wild-type but not Sting−/− mice, confirming that diABZI STING agonist-1 induces STING-dependent activation of type-I interferon and pro-inflammatory cytokines in vivo[1]. |
| References |
| Molecular Formula | C42H51N13O7 |
|---|---|
| Molecular Weight | 849.94 |
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Name: Agonist activity at human wild type STING
Source: ChEMBL
Target: Stimulator of interferon genes protein
External Id: CHEMBL5116574
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Name: Cytotoxicity against human wild type THP1-Dual cells assessed as residual cell viabil...
Source: ChEMBL
Target: THP1-Dual
External Id: CHEMBL5162240
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Name: Displacement of F-c-di-GMP from human STING expressed in Escherichia coli Rosetta 2(p...
Source: ChEMBL
Target: Stimulator of interferon genes protein
External Id: CHEMBL5329333
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Name: Induction of INF-beta secretion in human THP-1 cells assessed as maximal efficacy by ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5162285
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Name: Activation of NF-kappaB mediated pro-inflammatory effector proteins in mouse RAW264.7...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5162287
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Name: Activation of NF-kappaB mediated pro-inflammatory effector proteins in human THP-1 ce...
Source: ChEMBL
Target: Nuclear factor NF-kappa-B p100 subunit
External Id: CHEMBL5162286
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Name: Agonist activity at STING in mouse RAW-Lucia ISG cells assessed as ISG activation inc...
Source: ChEMBL
Target: Stimulator of interferon genes protein
External Id: CHEMBL5116538
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Name: Observed MRT infinity in rat at 1 mg/kg, iv
Source: ChEMBL
Target: N/A
External Id: CHEMBL4808266
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Name: Observed volume of distribution at steady state in rat at 1 mg/kg, iv
Source: ChEMBL
Target: N/A
External Id: CHEMBL4808267
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Name: Observed AUCinfinity in rat at 1 mg/kg, iv
Source: ChEMBL
Target: N/A
External Id: CHEMBL4808264
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