HS79

Modify Date: 2024-01-06 13:17:51

HS79 Structure
HS79 structure
Common Name HS79
CAS Number 2138838-56-7 Molecular Weight 338.47
Density N/A Boiling Point N/A
Molecular Formula C19H22N4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of HS79


HS-79 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-79 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 1.57 μM.

 Names

Name HS79

 HS79 Biological Activity

Description HS-79 is an enantiomer of Fasnall, which is a selective fatty acid synthase (FASN) inhibitor. HS-79 is able to inhibit the incorporation of tritiated acetate into lipids with an IC50 of 1.57 μM.
Related Catalog
Target

FASN[1]

In Vitro Fasnall, a thiophenopyrimidine selectively targeting FASN through its co-factor binding sites. Fasnall has anti-proliferative activity and induces apoptosis in breast cancer cells[1].
References

[1]. Alwarawrah Y, et al. Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer. Cell Chem Biol. 2016 Jun 23;23(6):678-88.

 Chemical & Physical Properties

Molecular Formula C19H22N4S
Molecular Weight 338.47
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.