N-Methylguanosine

Modify Date: 2024-01-02 14:47:46

N-Methylguanosine Structure
N-Methylguanosine structure
Common Name N-Methylguanosine
CAS Number 2140-77-4 Molecular Weight 297.267
Density 2.0±0.1 g/cm3 Boiling Point 709.5ºC at 760mmHg
Molecular Formula C11H15N5O5 Melting Point 233 °C (decomp)(Solv: water (7732-18-5))
MSDS Chinese USA Flash Point 382.9ºC

 Use of N-Methylguanosine


N2-methylguanosine is a modified nucleoside that occurs at several specific locations in many tRNA's.

 Names

Name n2-methylguanosine
Synonym More Synonyms

 N-Methylguanosine Biological Activity

Description N2-methylguanosine is a modified nucleoside that occurs at several specific locations in many tRNA's.
Related Catalog
References

[1]. Ginell SL, et al. Conformation of N2-methylguanosine, a modified nucleoside of tRNA. Biochem Biophys Res Commun. 1978 Oct 30;84(4):886-94.

 Chemical & Physical Properties

Density 2.0±0.1 g/cm3
Boiling Point 709.5ºC at 760mmHg
Melting Point 233 °C (decomp)(Solv: water (7732-18-5))
Molecular Formula C11H15N5O5
Molecular Weight 297.267
Flash Point 382.9ºC
Exact Mass 297.107330
PSA 145.52000
LogP -3.09
Vapour Pressure 3.99E-21mmHg at 25°C
Index of Refraction 1.850
Storage condition 2-8°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

 Articles33

More Articles
Exometabolom analysis of breast cancer cell lines: Metabolic signature.

Sci. Rep. 5 , 13374, (2015)

Cancer cells show characteristic effects on cellular turnover and DNA/RNA modifications leading to elevated levels of excreted modified nucleosides. We investigated the molecular signature of differen...

Artificial receptors for the extraction of nucleoside metabolite 7-methylguanosine from aqueous media made by molecular imprinting.

J. Chromatogr. A. 1365 , 12-8, (2014)

A series of imprinted polymers targeting nucleoside metabolites, prepared using a template analogue approach, are presented. These were prepared following selection of the optimum functional monomer b...

Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase.

Proc. Natl. Acad. Sci. U. S. A. 106 , 3484-3489, (2009)

The N7-methylguanosine (m7G) cap is the defining structural feature of eukaryotic mRNAs. Most eukaryotic viruses that replicate in the cytoplasm, including coronaviruses, have evolved strategies to ca...

 Synonyms

2-Methylguanosine
Guanosine, N-methyl-
N-Methylguanosine
Guanosine,N-methyl
9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-methylamino-3H-purin-6-one
2-N-Methylguanosine
N(2)-Methylguanosine
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