Prucalopride-13C,d3

Modify Date: 2024-01-08 07:35:53

Prucalopride-13C,d3 structure	Common Name	Prucalopride-13C,d3
	CAS Number	2140306-00-7	Molecular Weight	371.88
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇₁₃CH₂₃D₃ClN₃O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Prucalopride-13C,d3

Prucalopride-13C,d3 is the 13C- and deuterium labeled.

Name	Prucalopride-13C,d3

Description	Prucalopride-13C,d3 is the 13C- and deuterium labeled.
Related Catalog	Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[24].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. [2]. Briejer MR, et al. The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound. Eur J Pharmacol. 2001 Jun 29;423(1):71-83. [3]. Emmanuel AV, et al. Randomised clinical trial: the efficacy of prucalopride in patients with chronic intestinal pseudo-obstruction--a double-blind, placebo-controlled, cross-over, multiple n = 1 study. Aliment Pharmacol Ther. 2012 Jan;35(1):48-55. [4]. Bouras EP, et al. Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humans. Gut. 1999 May;44(5):682-6.

Molecular Formula	C₁₇₁₃CH₂₃D₃ClN₃O₃
Molecular Weight	371.88

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Shanghai Nianxing Industrial Co., Ltd
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Product Name: Prucalopride-13C,d3
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