5-Aminouridine
Modify Date: 2024-04-04 12:56:14
5-Aminouridine structure
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Common Name | 5-Aminouridine | ||
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| CAS Number | 2149-76-0 | Molecular Weight | 259.21600 | |
| Density | 1.712g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C9H13N3O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 5-Aminouridine5-Aminouridine can modify nucleobases and can be incorporated into the target DNA. 5-Aminouridine exhibits a wide range of biological activity and it inhibits the growth of tumors, fungi and viruses[1][2][3]. |
| Name | 5-amino-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione |
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| Synonym | More Synonyms |
| Description | 5-Aminouridine can modify nucleobases and can be incorporated into the target DNA. 5-Aminouridine exhibits a wide range of biological activity and it inhibits the growth of tumors, fungi and viruses[1][2][3]. |
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| Related Catalog | |
| In Vitro | This modified nucleobase, 5-Aminouridine, must exhibit a low enough potential to be oxidized by Os(bpy)33+. These modified nucleobases can be inserted into the target DNA by direct synthesis using modified phosphoramidites[4]. |
| In Vivo | 5-Aminouridine inhibits incorporation of carbamylaspartate into pyrimidines of both RNA and DNA in rat lived and [32P]phosphate into phospholipids and RNA nucleotides of rat liver slices and hepatoma[1]. |
| References |
[1]. Smith DA, et al. Studies on 5-aminouridine. Biochim Biophys Acta. 1966 May 19;119(2):221-8. |
| Density | 1.712g/cm3 |
|---|---|
| Molecular Formula | C9H13N3O6 |
| Molecular Weight | 259.21600 |
| Exact Mass | 259.08000 |
| PSA | 150.80000 |
| Index of Refraction | 1.666 |
| WGK Germany | 3 |
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| HS Code | 2934999090 |
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~80%
5-Aminouridine CAS#:2149-76-0 |
| Literature: Repkova; Ivanova; Komarova; Meshchaninova; Kuznetsova; Venyaminova Russian Journal of Bioorganic Chemistry, 1999 , vol. 25, # 9 p. 612 - 622 |
| Precursor 1 | |
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| DownStream 0 | |
| HS Code | 2934999090 |
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| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| 5-amino-uridine |
| Uridine,5-amino |
| 5-Aminouridin |