(2R,5S)-1-benzyl-2,5-dimethylpiperazine

Modify Date: 2024-01-02 14:04:02

(2R,5S)-1-benzyl-2,5-dimethylpiperazine Structure
(2R,5S)-1-benzyl-2,5-dimethylpiperazine structure
Common Name (2R,5S)-1-benzyl-2,5-dimethylpiperazine
CAS Number 216532-43-3 Molecular Weight 204.31100
Density 0.964g/cm3 Boiling Point 291.506ºC at 760 mmHg
Molecular Formula C13H20N2 Melting Point N/A
MSDS N/A Flash Point 109.461ºC

 Names

Name (2R,5S)-1-benzyl-2,5-dimethylpiperazine
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.964g/cm3
Boiling Point 291.506ºC at 760 mmHg
Molecular Formula C13H20N2
Molecular Weight 204.31100
Flash Point 109.461ºC
Exact Mass 204.16300
PSA 15.27000
LogP 2.13550
Vapour Pressure 0.002mmHg at 25°C
Index of Refraction 1.516

 Synthetic Route

~81%

(2R,5S)-1-benzyl-2,5-dimethylpiperazine Structure

(2R,5S)-1-benzy...

CAS#:216532-43-3

Literature: BRISTOL-MYERS SQUIBB COMPANY Patent: WO2005/40136 A1, 2005 ; Location in patent: Page/Page column 78-79 ; WO 2005/040136 A1

~99%

(2R,5S)-1-benzyl-2,5-dimethylpiperazine Structure

(2R,5S)-1-benzy...

CAS#:216532-43-3

Literature: KOWA COMPANY, LTD. Patent: US2010/280013 A1, 2010 ; Location in patent: Page/Page column 28 ;

~%

(2R,5S)-1-benzyl-2,5-dimethylpiperazine Structure

(2R,5S)-1-benzy...

CAS#:216532-43-3

Literature: WO2008/96260 A1, ; Page/Page column 41 ; WO 2008/096260 A1

~%

(2R,5S)-1-benzyl-2,5-dimethylpiperazine Structure

(2R,5S)-1-benzy...

CAS#:216532-43-3

Literature: Journal of Medicinal Chemistry, , vol. 43, # 2 p. 236 - 249

~%

(2R,5S)-1-benzyl-2,5-dimethylpiperazine Structure

(2R,5S)-1-benzy...

CAS#:216532-43-3

Literature: Journal of Medicinal Chemistry, , vol. 43, # 2 p. 236 - 249

~%

(2R,5S)-1-benzyl-2,5-dimethylpiperazine Structure

(2R,5S)-1-benzy...

CAS#:216532-43-3

Literature: Journal of Medicinal Chemistry, , vol. 42, # 15 p. 2741 - 2746

 Synonyms

N-benzyl-2R,5S-dimethylpiperazine
3-pyrimidin-2-yl-acrylonitrile
trans-2S,5R-dimethyl-4-benzyl-piperazine