N-(5-ADAMANTANE-1-YL-METHOXY)-PENTYL-DEOXYNOJIRIMYCIN

Modify Date: 2024-02-07 18:08:44

N-(5-ADAMANTANE-1-YL-METHOXY)-PENTYL-DEOXYNOJIRIMYCIN structure	Common Name	N-(5-ADAMANTANE-1-YL-METHOXY)-PENTYL-DEOXYNOJIRIMYCIN
	CAS Number	216758-20-2	Molecular Weight	397.549
	Density	1.2±0.1 g/cm3	Boiling Point	569.9±50.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₃₉NO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	298.4±30.1 °C

Use of N-(5-ADAMANTANE-1-YL-METHOXY)-PENTYL-DEOXYNOJIRIMYCIN

AMP-Deoxynojirimycin (AMP-DNM) is a potent ceramide glucosyltransferase and GCase 2 inhibitor. AMP-Deoxynojirimycin also is a GlcCer biosynthesis inhibitor[1][2].

Name	AMP-Deoxynojirimycin
Synonym	More Synonyms

Description	AMP-Deoxynojirimycin (AMP-DNM) is a potent ceramide glucosyltransferase and GCase 2 inhibitor. AMP-Deoxynojirimycin also is a GlcCer biosynthesis inhibitor[1][2].
Related Catalog	Research Areas >> Neurological Disease
In Vitro	AMP-Deoxynojirimycin (10 μM) significantly blocks the leucine and C17ISO-induced P70S6K phosphorylation in 3T3-L1 cells[1].
References	[1]. Zhu M, et al. Monomethyl branched-chain fatty acid mediates amino acid sensing upstream of mTORC1. Dev Cell. 2021 Oct 11;56(19):2692-2702.e5. [2]. Bae EJ, et al. Loss of glucocerebrosidase 1 activity causes lysosomal dysfunction and α-synuclein aggregation. Exp Mol Med. 2015 Mar 27;47(3):e153.

Density	1.2±0.1 g/cm3
Boiling Point	569.9±50.0 °C at 760 mmHg
Molecular Formula	C₂₂H₃₉NO₅
Molecular Weight	397.549
Flash Point	298.4±30.1 °C
Exact Mass	397.282837
PSA	93.39000
LogP	3.04
Vapour Pressure	0.0±3.6 mmHg at 25°C
Index of Refraction	1.570

(2R,3R,4R,5S)-1-{5-[(3s,5s,7s)-Adamantan-1-ylmethoxy]pentyl}-2-(hydroxymethyl)-3,4,5-piperidinetriol

(2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)pentyl]-2-(hydroxymethyl)-3,4,5-piperidinetriol

3,4,5-Piperidinetriol, 2-(hydroxymethyl)-1-[5-(tricyclo[3.3.1.1]dec-1-ylmethoxy)pentyl]-, (2R,3R,4R,5S)-

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: N-(5-ADAMANTANE-1-YL-METHOXY)-PENTYL-DEOXYNOJIRIMYCIN
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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N-(5-ADAMANTANE-1-YL-METHOXY)-PENTYL-DEOXYNOJIRIMYCIN

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