Tadnersen

Modify Date: 2024-01-10 12:40:11

Tadnersen Structure
Tadnersen structure
Common Name Tadnersen
CAS Number 2170507-65-8 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tadnersen


Tadnersen (BIIB078), an antisense oligonucleotide (ASO), selectively targets C9ORF72 transcript variants 1 and 3 that carry the expansion[1].

 Names

Name Tadnersen

 Tadnersen Biological Activity

Description Tadnersen (BIIB078), an antisense oligonucleotide (ASO), selectively targets C9ORF72 transcript variants 1 and 3 that carry the expansion[1].
Related Catalog
In Vitro Tadnersen (BIIB078) is an RNAse H oligomer that selectively inhibits mutant C9ORF72 transcripts. Tadnersen is used for the research of Amyotrophic Lateral Sclerosis (ALS)[2].
References

[1]. Smeyers J, et al. C9ORF72: What It Is, What It Does, and Why It Matters. Front Cell Neurosci. 2021;15:661447. Published 2021 May 5.

[2]. Aoki Y, et al. Emerging Oligonucleotide Therapeutics for Rare Neuromuscular Diseases [published online ahead of print, 2021 Jun 3]. J Neuromuscul Dis. 2021;10.3233/JND-200560.

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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