AGH-107

Modify Date: 2025-11-21 11:21:31

AGH-107 Structure
AGH-107 structure
Common Name AGH-107
CAS Number 2172907-10-5 Molecular Weight 337.164
Density N/A Boiling Point N/A
Molecular Formula C13H12In3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AGH-107


AGH-107 is a potent, selective 5-HT7 receptor agonist with Ki of 6 nM and EC50 of 19 nM, 176-fold selectivity over 5-HT1AR.AGH-107 exhibited high selectivity over related CNS targets, high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures.

 Names

Name AGH-107

 AGH-107 Biological Activity

Description AGH-107 is a potent, selective 5-HT7 receptor agonist with Ki of 6 nM and EC50 of 19 nM, 176-fold selectivity over 5-HT1AR.AGH-107 exhibited high selectivity over related CNS targets, high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures.
References 1. Hogendorf AS, et al. Sci Rep. 2017 May 4;7(1):1444.

 Chemical & Physical Properties

Molecular Formula C13H12In3
Molecular Weight 337.164
InChIKey JLCILCCDUVFIRF-UHFFFAOYSA-N
SMILES CCn1cncc1-c1c[nH]c2ccc(I)cc12
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