FAM hydrazide 5-isomer

Modify Date: 2024-01-13 11:50:10

FAM hydrazide 5-isomer Structure
FAM hydrazide 5-isomer structure
Common Name FAM hydrazide 5-isomer
CAS Number 2183440-64-2 Molecular Weight 426.807
Density N/A Boiling Point N/A
Molecular Formula C21H15ClN2O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FAM hydrazide 5-isomer


Many natural and synthetic molecules contain aldehyde or ketone carbonyl groups. These carbonyls react with hydrazides with the formation of hydrazones. The reaction is spontaneous at pH values around neutral, and the resulting hydrazones are very stable. Compounds containing 1,2-diol function, like sugars, can be oxidized with sodium periodate with the formation of carbonyl compounds for the subsequent modification with hydrazides. This is an efficient method for the labeling of glycoproteins (like antibodies), and polysaccharides. FAM hydrazide is a hydrazide label for the attachment of fluorescein, a bright dye for 488 nm channel, to carbonyl compounds

 Names

Name [(3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthen]-5-yl)carbonyl]hydrazinium chloride
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C21H15ClN2O6
Molecular Weight 426.807
Exact Mass 426.061859

 Synonyms

[(3',6'-Dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthen]-5-yl)carbonyl]hydrazinium chloride
Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-5-carboxylic acid, 3',6'-dihydroxy-3-oxo-, hydrazide, hydrochloride (1:1)