Falcarinol

Modify Date: 2025-08-20 20:02:39

Falcarinol Structure
Falcarinol structure
 Common Name Falcarinol
CAS Number 21852-80-2 Molecular Weight 244.372
Density 0.9±0.1 g/cm3 Boiling Point 370.6±42.0 °C at 760 mmHg
Molecular Formula C17H24O Melting Point N/A
MSDS N/A Flash Point 163.4±20.9 °C

 Use of Falcarinol


Falcarinol (Panaxynol) is a natural, orally active Hsp90 inhibitor targeting both the N-terminal and C-terminal of Hsp90 with limited toxicities. Falcarinol (Panaxynol) induces apoptosis[1].

 Names

Name 1,9-Heptadecadiene-4,6-diyn-3-ol
Synonym More Synonyms

 Falcarinol Biological Activity

Description Falcarinol (Panaxynol) is a natural, orally active Hsp90 inhibitor targeting both the N-terminal and C-terminal of Hsp90 with limited toxicities. Falcarinol (Panaxynol) induces apoptosis[1].
Related Catalog
In Vitro Panaxynol inhibits the sphere-forming ability of NSCLC CSCs by inducing apoptosis. Panaxynol suppresses the viability of NSCLC cells with no effects on normal cells[1].
References

[1]. Le HT, et al. Panaxynol, a natural Hsp90 inhibitor, effectively targets both lung cancer stem and non-stem cells. Cancer Lett. 2018 Jan 1;412:297-307.

 Chemical & Physical Properties

Density 0.9±0.1 g/cm3
Boiling Point 370.6±42.0 °C at 760 mmHg
Molecular Formula C17H24O
Molecular Weight 244.372
Flash Point 163.4±20.9 °C
Exact Mass 244.182709
PSA 20.23000
LogP 6.96
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.507

 Safety Information

HS Code 2905290000

 Synthetic Route

1-chlorodec-2-ene structure

1-chlorodec-2-ene

CAS#:135457-18-0

N/A structure

N/A

CAS#:405144-99-2

~69%

Falcarinol Structure

Falcarinol

CAS#:21852-80-2

Literature: Mayer, Sandra F.; Steinreiber, Andreas; Orru, Romano V. A.; Faber, Kurt Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9115 - 9121
N/A structure

N/A

CAS#:1262023-34-6

~40%

N/A structure

N/A

CAS#:1262023-37-9

Falcarinol Structure

Falcarinol

CAS#:21852-80-2

Literature: McLaughlin, Noel P.; Butler, Eibhlin; Evans, Paul; Brunton, Nigel P.; Koidis, Anastasios; Rai, Dilip K. Tetrahedron, 2010 , vol. 66, # 51 p. 9681 - 9687
2-Decyn-1-ol structure

2-Decyn-1-ol

CAS#:4117-14-0

~%

Falcarinol Structure

Falcarinol

CAS#:21852-80-2

Literature: Mayer, Sandra F.; Steinreiber, Andreas; Orru, Romano V. A.; Faber, Kurt Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9115 - 9121
hept-1-en-4,6-diyn-3-ol structure

hept-1-en-4,6-d...

CAS#:14304-31-5

~%

Falcarinol Structure

Falcarinol

CAS#:21852-80-2

Literature: Mayer, Sandra F.; Steinreiber, Andreas; Orru, Romano V. A.; Faber, Kurt Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9115 - 9121
N/A structure

N/A

CAS#:4194-71-2

~%

Falcarinol Structure

Falcarinol

CAS#:21852-80-2

Literature: Mayer, Sandra F.; Steinreiber, Andreas; Orru, Romano V. A.; Faber, Kurt Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9115 - 9121
(3R)-hept-1-ene-4,6-diyn-3-ol acetate structure

(3R)-hept-1-ene...

CAS#:405144-92-5

~%

Falcarinol Structure

Falcarinol

CAS#:21852-80-2

Literature: Mayer, Sandra F.; Steinreiber, Andreas; Orru, Romano V. A.; Faber, Kurt Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9115 - 9121
4-hydroxy-2-methyleneheptanal structure

4-hydroxy-2-met...

CAS#:445494-03-1

~%

Falcarinol Structure

Falcarinol

CAS#:21852-80-2

Literature: Mayer, Sandra F.; Steinreiber, Andreas; Orru, Romano V. A.; Faber, Kurt Journal of Organic Chemistry, 2002 , vol. 67, # 26 p. 9115 - 9121
3(R)-(tert-butyldiphenylsilyloxy)-1-penten-4-yne structure

3(R)-(tert-buty...

CAS#:224636-36-6

~%

Falcarinol Structure

Falcarinol

CAS#:21852-80-2

Literature: Zheng, Guangrong; Lu, Wei; Aisa, Haji A.; Cai, Junchao Tetrahedron Letters, 1999 , vol. 40, # 11 p. 2181 - 2182

 Customs

HS Code 2905290000
Summary 2905290000 unsaturated monohydric alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Synonyms

Carotatoxin
(-)-Falcarinol
(-)-Carotatoxin
1,9-Heptadecadiene-4,6-diyn-3-ol, (3R,9Z)-
(-)-Panaxynol
(−)-(3R)-falcarinol
(3R,9Z)-1,9-Heptadecadiene-4,6-diyn-3-ol
Falcarinol
Panaxynol
(3R,9Z)-Heptadeca-1,9-diene-4,6-diyn-3-ol
Falcarinol
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