Isoescin IB structure
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Common Name | Isoescin IB | ||
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CAS Number | 219944-46-4 | Molecular Weight | 1131.257 | |
Density | 1.5±0.1 g/cm3 | Boiling Point | 1148.1±65.0 °C at 760 mmHg | |
Molecular Formula | C55H86O24 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 314.2±27.8 °C |
Use of Isoescin IBIsoescin IB, isolated from horse chestnut tree seeds, is an isomer of Escin IB. Isoescin IB and Escin IB are the chief active ingredients in escin[1]. |
Name | (3β,16α,21β,22α)-28-Acetoxy-16,22,24-trihydroxy-21-{[(2Z)-2-methylbut-2-enoyl]oxy}olean-12-en-3-yl β-D-glucopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->4)]-β-D-glucopyranosiduronic acid |
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Synonym | More Synonyms |
Description | Isoescin IB, isolated from horse chestnut tree seeds, is an isomer of Escin IB. Isoescin IB and Escin IB are the chief active ingredients in escin[1]. |
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Related Catalog | |
In Vitro | β-Escin (mainly consisting of escin Ia and escin Ib) is the major active ingredient in horse chestnut seeds extracts. β-escin can inhibit proliferation and/or induce apoptosis in various types of cancer cells including A549 cell, HT-29 cell, HCC cell, OVCAR3 cell and H-Ras 5RP7 cell. β-escin may be useful as a chemopreventive agent, especially for tumors associated with an inflammatory response[1]. As the minor component of escin, α-escin (mainly consisting of isoescin Ia and isoescin Ib) exhibits lower bioactivity[1]. |
References |
Density | 1.5±0.1 g/cm3 |
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Boiling Point | 1148.1±65.0 °C at 760 mmHg |
Molecular Formula | C55H86O24 |
Molecular Weight | 1131.257 |
Flash Point | 314.2±27.8 °C |
Exact Mass | 1130.550903 |
LogP | 2.17 |
Vapour Pressure | 0.0±0.6 mmHg at 25°C |
Index of Refraction | 1.628 |
2-butenoic acid, 2-methyl-, (3β,16α,21β,22α)-28-(acetyloxy)-3-[[O-β-D-glucopyranosyl-(1->2)-O-[β-D-glucopyranosyl-(1->4)]-β-D-glucopyranuronosyl]oxy]-16,22,24-trihydroxyolean-12-en-21-yl ester, (2Z)- |
(3β,16α,21β,22α)-28-Acetoxy-16,22,24-trihydroxy-21-{[(2Z)-2-methylbut-2-enoyl]oxy}olean-12-en-3-yl β-D-glucopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->4)]-β-D-glucopyranosiduronic acid |
2-Butenoic acid, 2-methyl-, (3β,16α,21β,22α)-28-(acetyloxy)-3-[[O-β-D-glucopyranosyl-(1->2)-O-[β-D-glucopyranosyl-(1->4)]-β-D-glucopyranuronosyl]oxy]-16,22,24-trihydroxyolean-12 
-en-21-yl ester, (2Z)- |
Aescin D |
Escin IVb |
Isoescin Ib |