1,4-Benzodioxan-6-amine

Modify Date: 2025-08-27 17:48:34

1,4-Benzodioxan-6-amine Structure
1,4-Benzodioxan-6-amine structure
Common Name 1,4-Benzodioxan-6-amine
CAS Number 22013-33-8 Molecular Weight 151.16300
Density 1.231 g/mL at 25 °C(lit.) Boiling Point 116-118°C 3mm
Molecular Formula C8H9NO2 Melting Point 29-31 °C(lit.)
MSDS Chinese USA Flash Point >230 °F
Symbol GHS07
GHS07
Signal Word Warning

 Use of 1,4-Benzodioxan-6-amine




 Names

Name 2,3-dihydro-1,4-benzodioxin-6-amine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.231 g/mL at 25 °C(lit.)
Boiling Point 116-118°C 3mm
Melting Point 29-31 °C(lit.)
Molecular Formula C8H9NO2
Molecular Weight 151.16300
Flash Point >230 °F
Exact Mass 151.06300
PSA 44.48000
LogP 1.62120
Vapour Pressure 0.0017mmHg at 25°C
Index of Refraction n20/D 1.599(lit.)
Water Solubility insoluble

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302 + H312 + H332-H315-H319-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xn:Harmful;
Risk Phrases R20/21/22;R38
Safety Phrases S26-S37/39-S36/37
RIDADR 2810
WGK Germany 3
Packaging Group III
Hazard Class 6.1
HS Code 29329995

 Synthetic Route

~91%

1,4-Benzodioxan-6-amine Structure

1,4-Benzodioxan...

CAS#:22013-33-8

Literature: Dey, Raju; Mukherjee, Nirmalya; Ahammed, Sabir; Ranu, Brindaban C. Chemical Communications, 2012 , vol. 48, # 64 p. 7982 - 7984

~56%

1,4-Benzodioxan-6-amine Structure

1,4-Benzodioxan...

CAS#:22013-33-8

Literature: Zorina, L. N.; Safiev, O. G.; Rakhmankulov, D. L.; Paushkin, Ya. M. Doklady Chemistry, 1987 , vol. 296, # 10 p. 444 - 446 Dokl. Akad. Nauk SSSR Ser. Khim., 1987 , vol. 296, # 4 p. 887 - 890

~89%

1,4-Benzodioxan-6-amine Structure

1,4-Benzodioxan...

CAS#:22013-33-8

Literature: Mateu; Capilla; Harrak; Pujol Tetrahedron, 2002 , vol. 58, # 26 p. 5241 - 5250

~66%

1,4-Benzodioxan-6-amine Structure

1,4-Benzodioxan...

CAS#:22013-33-8

Literature: Romero; Harrak; Basset; Orue; Pujol Tetrahedron, 2009 , vol. 65, # 10 p. 1951 - 1956

~%

1,4-Benzodioxan-6-amine Structure

1,4-Benzodioxan...

CAS#:22013-33-8

Literature: Russian Chemical Bulletin, , vol. 58, # 6 p. 1233 - 1240

~%

1,4-Benzodioxan-6-amine Structure

1,4-Benzodioxan...

CAS#:22013-33-8

Literature: Journal of Organic Chemistry, , vol. 49, # 22 p. 4295 - 4297

 Preparation


 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles2

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J. Heterocycl. Chem. 47(6) , 1275-1282, (2010)

Novel arylamino alcohols were synthesized and these alcohols were used to prepare 12 novel N-(2-hydroxy-ethyl)-2,3-didehydroazapodophyllotoxins, in one step, by simple reflux in ethanol. Isolated yiel...

2, 3-Dihydrodioxin [2, 3-b] acridin-11 (6H)-one. Karolak-Wojciechowska J, et al.

Acta Crystallogr. C 54(11) , 1689-90, (1998)

 Synonyms

6-Amino-1,4-benzodioxane
3,4-Ethylenedioxyaniline
2,3-Dihydrobenzo[b][1,4]dioxin-6-amine
6-Amino-1,4-benzodioxan
2,3-dihydro-1,4-benzodioxin-6-amin
1,4-Benzodioxan-6-amine
MFCD00006824
EINECS 244-718-4
6-amino-2,3-dihydro-1,4-benzodioxin
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