UR-3216 structure
|
Common Name | UR-3216 | ||
|---|---|---|---|---|
| CAS Number | 220386-65-2 | Molecular Weight | 563.56 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H29N7O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of UR-3216UR-3216, a prodrug, is a selective and orally active platelet surface glycoprotein (GPIIb/IIIa) receptor antagonist. UR-3216 is the very tight binding of its active metabolite to platelets (Ki for resting platelets is < 1 nM). UR-2992, the active form of UR-3216, binds to platelets for a long period of time, while the unbound drug is rapidly cleared. |
This table lists Chinese names, IUPAC names and various aliases of this chemical substance.
| Name | UR-3216 |
|---|
This table contains bioactivity, target information and biological‑assay experimental data of this compound.
| Description | UR-3216, a prodrug, is a selective and orally active platelet surface glycoprotein (GPIIb/IIIa) receptor antagonist. UR-3216 is the very tight binding of its active metabolite to platelets (Ki for resting platelets is < 1 nM). UR-2992, the active form of UR-3216, binds to platelets for a long period of time, while the unbound drug is rapidly cleared. |
|---|---|
| References | 1. Aga Y, Baba K, Tam S, Nakanishi T, Yoneda K, Kita J, Ueno H. UR-3216: a new generation oral platelet GPIIb/IIIa antagonist. Curr Pharm Des. 2004;10(14):1597-601. Review. PubMed PMID: 15134558. |
This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.
| Molecular Formula | C27H29N7O7 |
|---|---|
| Molecular Weight | 563.56 |
| InChIKey | JFXRCSVTAOUYGR-QHCPKHFHSA-N |
| SMILES | CCOC(=O)Cn1cc2c(n1)CCN(C(=O)C(Cc1ccc([N+](=O)[O-])cc1)NC(=O)c1ccc(C(N)=NO)cc1)C2 |
This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.
| Q: What is the English name of UR-3216? |
| A: The English name of UR-3216 is UR-3216. |
| Q: What is the molecular formula of UR-3216? |
| A: Molecular formula of UR-3216 is C27H29N7O7. |
| Q: What is the Chinese name of 220386-65-2? |
| A: Chinese name of 220386-65-2 is 220386-65-2. |
| Q: What is the molecular weight of UR-3216? |
| A: Molecular weight of UR-3216 is 563.56. |
| Q: What is the CAS number of UR-3216? |
| A: CAS number of UR-3216 is 220386-65-2. |
| Q: What is the SMILES notation of UR-3216? |
| A: SMILES notation of UR-3216 is CCOC(=O)Cn1cc2c(n1)CCN(C(=O)C(Cc1ccc([N+](=O)[O-])cc1)NC(=O)c1ccc(C(N)=NO)cc1)C2. |
| Q: What are the uses of UR-3216? |
| A: Main uses of UR-3216: UR-3216, a prodrug, is a selective and orally active platelet surface glycoprotein (GPIIb/IIIa) receptor antagonist. UR-3216 is the very tight binding of its active metabolite to platelets (Ki for resting platelets is < 1 nM). UR-2992, the active form of UR-3216, binds to platelets for a long period of time, while the unbound drug is rapidly cleared. |
| Q: What is the InChIKey of UR-3216? |
| A: InChIKey of UR-3216 is JFXRCSVTAOUYGR-QHCPKHFHSA-N. |