UR-3216
Modify Date: 2025-09-26 12:51:07
UR-3216 structure
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Common Name | UR-3216 | ||
|---|---|---|---|---|
| CAS Number | 220386-65-2 | Molecular Weight | 563.56 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C27H29N7O7 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of UR-3216UR-3216, a prodrug, is a selective and orally active platelet surface glycoprotein (GPIIb/IIIa) receptor antagonist. UR-3216 is the very tight binding of its active metabolite to platelets (Ki for resting platelets is < 1 nM). UR-2992, the active form of UR-3216, binds to platelets for a long period of time, while the unbound drug is rapidly cleared. |
| Name | UR-3216 |
|---|
| Description | UR-3216, a prodrug, is a selective and orally active platelet surface glycoprotein (GPIIb/IIIa) receptor antagonist. UR-3216 is the very tight binding of its active metabolite to platelets (Ki for resting platelets is < 1 nM). UR-2992, the active form of UR-3216, binds to platelets for a long period of time, while the unbound drug is rapidly cleared. |
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| References | 1. Aga Y, Baba K, Tam S, Nakanishi T, Yoneda K, Kita J, Ueno H. UR-3216: a new generation oral platelet GPIIb/IIIa antagonist. Curr Pharm Des. 2004;10(14):1597-601. Review. PubMed PMID: 15134558. |
| Molecular Formula | C27H29N7O7 |
|---|---|
| Molecular Weight | 563.56 |
| InChIKey | JFXRCSVTAOUYGR-QHCPKHFHSA-N |
| SMILES | CCOC(=O)Cn1cc2c(n1)CCN(C(=O)C(Cc1ccc([N+](=O)[O-])cc1)NC(=O)c1ccc(C(N)=NO)cc1)C2 |