MY10
Modify Date: 2025-09-21 01:24:41
MY10 structure
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Common Name | MY10 | ||
|---|---|---|---|---|
| CAS Number | 2204270-73-3 | Molecular Weight | 384.354 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H10F6OS2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MY10MY10 is a small-molecule inhibitor of RPTPβ/ζ (PTPRZ1) with IC50 of 0.1 uM, significantly increases the phosphorylation of key tyrosine residues of RPTPβ/ζ substrates involved in neuronal survival and differentiation; blocks ethanol conditioned place preference, shows limited effects on ethanol-induced ataxia, and potentiates the sedative effects of ethanol in mice; increases levels of phosphorylated ALK and TrkA in neuroblastoma cells, modulates signaling pathways activated by alcohol. |
| Name | MY10 |
|---|
| Description | MY10 is a small-molecule inhibitor of RPTPβ/ζ (PTPRZ1) with IC50 of 0.1 uM, significantly increases the phosphorylation of key tyrosine residues of RPTPβ/ζ substrates involved in neuronal survival and differentiation; blocks ethanol conditioned place preference, shows limited effects on ethanol-induced ataxia, and potentiates the sedative effects of ethanol in mice; increases levels of phosphorylated ALK and TrkA in neuroblastoma cells, modulates signaling pathways activated by alcohol. |
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| References | References 1. Fernández-Calle R, et al. Neuropharmacology. 2018 May 9;137:86-95. View Related Products by Target Protein Phosphatase/PTP |
| Molecular Formula | C15H10F6OS2 |
|---|---|
| Molecular Weight | 384.354 |
| InChIKey | OJUUGOMDHJFXJH-UHFFFAOYSA-N |
| SMILES | FC(F)(F)Sc1ccc(COc2ccc(SC(F)(F)F)cc2)cc1 |