5-Bromofuro[2,3-b]pyridine

Modify Date: 2024-01-02 16:21:30

5-Bromofuro[2,3-b]pyridine Structure
5-Bromofuro[2,3-b]pyridine structure
Common Name 5-Bromofuro[2,3-b]pyridine
CAS Number 220957-39-1 Molecular Weight 198.017
Density 1.7±0.1 g/cm3 Boiling Point 226.0±20.0 °C at 760 mmHg
Molecular Formula C7H4BrNO Melting Point N/A
MSDS USA Flash Point 90.5±21.8 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 5-Bromofuro[2,3-b]pyridine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 226.0±20.0 °C at 760 mmHg
Molecular Formula C7H4BrNO
Molecular Weight 198.017
Flash Point 90.5±21.8 °C
Exact Mass 196.947617
PSA 26.03000
LogP 2.25
Vapour Pressure 0.1±0.4 mmHg at 25°C
Index of Refraction 1.649

 MSDS


SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifiers
Product name: 5-Bromofuro[2,3-B]Pyridine
: ADE001191
REACH No.: A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not
require a registration or the registration is envisaged for a later
registration deadline.


SECTION 2: Hazards identification
Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral (Category 4), H302
For the full text of the H-Statements mentioned in this Section, see Section 16.
Classification according to EU Directives 67/548/EEC or 1999/45/EC
Xn HarmfulR22
For the full text of the R-phrases mentioned in this Section, see Section 16.
Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram
Signal wordWarning
Hazard statement(s)
Harmful if swallowed.
Precautionary statement(s)none
Supplemental Hazardnone
Statements
Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

SECTION 3: Composition/information on ingredients
Substances
Molecular weight: 198,02 g/mol
Hazardous ingredients according to Regulation (EC) No 1272/2008
ComponentClassificationConcentration
5-Bromofuro[2,3-B]Pyridine
Acute Tox. 4; H302<= 100 %
Hazardous ingredients according to Directive 1999/45/EC
ComponentClassificationConcentration
5-Bromofuro[2,3-B]Pyridine
Xn, R22<= 100 %
For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16

SECTION 4: First aid measures
Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
Indication of any immediate medical attention and special treatment needed
No data available

SECTION 5: Firefighting measures
Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Nature of decomposition products not known.
Advice for firefighters
Wear self-contained breathing apparatus for firefighting if necessary.
Further information
No data available

SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure
adequate ventilation. Avoid breathing dust.
For personal protection see section 8.
Environmental precautions
Do not let product enter drains.
Methods and materials for containment and cleaning up
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed
containers for disposal.
Reference to other sections
For disposal see section 13.

SECTION 7: Handling and storage
Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols.
Provide appropriate exhaust ventilation at places where dust is formed.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place.
Storage class (TRGS 510): Non Combustible Solids
Specific end use(s)
Apart from the uses mentioned in section 1.2 no other specific uses are stipulated

SECTION 8: Exposure controls/personal protection
Control parameters
Components with workplace control parameters
Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
at the end of workday.
Personal protective equipment
Eye/face protection
Safety glasses with side-shields conforming to EN166 Use equipment for eye protection tested
and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Body Protection
Complete suit protecting against chemicals, The type of protective equipment must be selected
according to the concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
For nuisance exposures use type P95 (US) or type P1 (EU EN 143) particle respirator.For higher
level protection use type OV/AG/P99 (US) or type ABEK-P2 (EU EN 143) respirator cartridges.
Use respirators and components tested and approved under appropriate government standards
such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Do not let product enter drains.

SECTION 9: Physical and chemical properties
Information on basic physical and chemical properties
a) AppearanceForm: solid
b) OdourNo data available
c) Odour ThresholdNo data available
d) pHNo data available
e) Melting point/freezingNo data available
point
f) Initial boiling point and No data available
boiling range
g) Flash pointNo data available
h) Evaporation rateNo data available
i) Flammability (solid, gas) No data available
j) Upper/lowerNo data available
flammability or
explosive limits
k) Vapour pressureNo data available
l) Vapour densityNo data available
m) Relative densityNo data available
n) Water solubilityNo data available
o) Partition coefficient: n- No data available
octanol/water
p) Auto-ignitionNo data available
temperature
q) DecompositionNo data available
temperature
r) ViscosityNo data available
s) Explosive propertiesNo data available
t) Oxidizing propertiesNo data available
Other safety information
No data available

SECTION 10: Stability and reactivity
Reactivity
No data available
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
No data available
Conditions to avoid
No data available
Incompatible materials
No data available
Hazardous decomposition products
In the event of fire: see section 5

SECTION 11: Toxicological information
Information on toxicological effects
Acute toxicity
No data available
Skin corrosion/irritation
No data available
Serious eye damage/eye irritation
No data available
Respiratory or skin sensitisation
No data available
Germ cell mutagenicity
No data available
Carcinogenicity
IARC:No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
No data available
Specific target organ toxicity - single exposure
No data available
Specific target organ toxicity - repeated exposure
No data available
Aspiration hazard
No data available
Additional Information
RTECS: Not available

SECTION 12: Ecological information
Toxicity
No data available
Persistence and degradability
No data available
Bioaccumulative potential
No data available
Mobility in soil
No data available
Results of PBT and vPvB assessment
This substance/mixture contains no components considered to be either persistent, bioaccumulative and
toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Other adverse effects
No data available

SECTION 13: Disposal considerations
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material
with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber.
Contaminated packaging
Dispose of as unused product.

SECTION 14: Transport information
UN number
ADR/RID: -IMDG: -IATA: -
UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA:Not dangerous goods
Transport hazard class(es)
ADR/RID: -IMDG: -IATA: -
Packaging group
ADR/RID: -IMDG: -IATA: -
Environmental hazards
ADR/RID: noIMDG Marine pollutant: noIATA: no
Special precautions for user
No data available

SECTION 15: Regulatory information
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
Safety, health and environmental regulations/legislation specific for the substance or mixture
No data available
Chemical Safety Assessment


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
RIDADR NONH for all modes of transport
HS Code 2934999090

 Synthetic Route

~32%

5-Bromofuro[2,3-b]pyridine Structure

5-Bromofuro[2,3...

CAS#:220957-39-1

Literature: SCHERING CORPORATION; DENG, Yongqi; SUN, Binyuan; ZENG, Hongbo; RICHARDS, Matthew; SHIPPS, Gerald, W., Jr.; CHENG, Cliff, C.; ZHAO, Yinyan; MCRINER, Andrew; MENG, Zhaoyang; NAN, Yang; PATEL, Mehul, F.; WRONA, Iwona, E.; REDDY, Panduranga, Adulla; EKLOV, Brian, M.; TANG, Shuyi; LIU, Duan; MANDAL, Amit, K.; ZHAO, Lianyun; SIDDIQUI, M., Arshad Patent: WO2010/118207 A1, 2010 ; Location in patent: Page/Page column 282-283 ; WO 2010/118207 A1

~%

5-Bromofuro[2,3-b]pyridine Structure

5-Bromofuro[2,3...

CAS#:220957-39-1

Literature: WO2007/71434 A1, ; Page/Page column 49 ;

~%

5-Bromofuro[2,3-b]pyridine Structure

5-Bromofuro[2,3...

CAS#:220957-39-1

Literature: Journal of Heterocyclic Chemistry, , vol. 35, # 6 p. 1305 - 1307

~%

5-Bromofuro[2,3-b]pyridine Structure

5-Bromofuro[2,3...

CAS#:220957-39-1

Literature: Journal of Heterocyclic Chemistry, , vol. 35, # 6 p. 1305 - 1307

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

5-bromofuro<2,3-b>pyridine
Furo[2,3-b]pyridine, 5-bromo-
5-Bromofuro[2,3-b]pyridine
QC-4108
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