Elomotecan hydrochloride

Modify Date: 2024-01-10 10:10:02

Elomotecan hydrochloride Structure
Elomotecan hydrochloride structure
Common Name Elomotecan hydrochloride
CAS Number 220997-99-9 Molecular Weight 558.50
Density N/A Boiling Point N/A
Molecular Formula C29H33Cl2N3O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Elomotecan hydrochloride


Elomotecan (hydrochloride) is a potent inhibitor of topoisomerases I and II. Elomotecan (hydrochloride) is a camptothecin analog belonging to the homocamptothecin family (hCPT). Elomotecan (hydrochloride) reduces the proliferation of different tumor cells with higher potency than other anticancer drugs of reference targeting topoisomerases I or II[1].

 Names

Name Elomotecan hydrochloride

 Elomotecan hydrochloride Biological Activity

Description Elomotecan (hydrochloride) is a potent inhibitor of topoisomerases I and II. Elomotecan (hydrochloride) is a camptothecin analog belonging to the homocamptothecin family (hCPT). Elomotecan (hydrochloride) reduces the proliferation of different tumor cells with higher potency than other anticancer drugs of reference targeting topoisomerases I or II[1].
Related Catalog
Target

Topoisomerase I

Topoisomerase II

References

[1]. Trocóniz IF, et al. Population pharmacokinetic/pharmacodynamic modeling of drug-induced adverse effects of a novel homocamptothecin analog, elomotecan (BN80927), in a Phase I dose finding study in patients with advanced solid tumors. Cancer Chemother Pharmacol. 2012;70(2):239-250.

 Chemical & Physical Properties

Molecular Formula C29H33Cl2N3O4
Molecular Weight 558.50
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