Methylswertianin

Modify Date: 2024-01-13 18:53:09

Methylswertianin Structure
Methylswertianin structure
Common Name Methylswertianin
CAS Number 22172-17-4 Molecular Weight 288.252
Density 1.5±0.1 g/cm3 Boiling Point 546.3±50.0 °C at 760 mmHg
Molecular Formula C15H12O6 Melting Point 191-192℃
MSDS N/A Flash Point 210.7±23.6 °C

 Use of Methylswertianin


Methylswertianin is an active constituent in Swertia punicea Hemsl, with anti-diabetic effect. Methylswertianin could be useful for treating type-2 diabetes, likely via the improvement of insulin resistance (IR)[1].

 Names

Name 2-O-methylswertianin
Synonym More Synonyms

 Methylswertianin Biological Activity

Description Methylswertianin is an active constituent in Swertia punicea Hemsl, with anti-diabetic effect. Methylswertianin could be useful for treating type-2 diabetes, likely via the improvement of insulin resistance (IR)[1].
Related Catalog
References

[1]. Tian LY, et al. Anti-diabetic effect of methylswertianin and bellidifolin from Swertia punicea Hemsl. and its potential mechanism. Phytomedicine. 2010 Jun;17(7):533-9.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 546.3±50.0 °C at 760 mmHg
Melting Point 191-192℃
Molecular Formula C15H12O6
Molecular Weight 288.252
Flash Point 210.7±23.6 °C
Exact Mass 288.063385
PSA 89.13000
LogP 1.66
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.653

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ZD6034200
CHEMICAL NAME :
Xanthen-9-one, 1,8-dihydroxy-2,6-dimethoxy-
CAS REGISTRY NUMBER :
22172-17-4
BEILSTEIN REFERENCE NO. :
1351740
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C15-H12-O6
MOLECULAR WEIGHT :
288.27

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
100 ug/plate
REFERENCE :
CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 32,2290,1984

 Safety Information

HS Code 2932999099

 Synthetic Route

~%

Methylswertianin Structure

Methylswertianin

CAS#:22172-17-4

Literature: Journal of the Indian Chemical Society, , vol. 72, # 1 p. 63 - 64

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

1,8-dihydroxy-2,6-dimethoxyxanthen-9-one
7-O-methyl swertianin
Swertiaperennin
Xanthen-9-one,1,8-dihydroxy-2,6-dimethoxy
metylswertianin
Methylswertianin
9H-Xanthen-9-one, 1,8-dihydroxy-2,6-dimethoxy-
1,8-Dihydroxy-2,6-dimethoxy-9H-xanthen-9-one
1,8-dihydroxy-3,7-dimethoxyxanthone
swertsiaperennin
1,8-Dihydroxy-2,6-dimethoxyxanthone
2-O-Methylswertianin
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