42-(2-Tetrazolyl)rapamycin

Modify Date: 2024-01-08 12:19:29

42-(2-Tetrazolyl)rapamycin Structure
42-(2-Tetrazolyl)rapamycin structure
Common Name 42-(2-Tetrazolyl)rapamycin
CAS Number 221877-56-1 Molecular Weight 966.21
Density N/A Boiling Point N/A
Molecular Formula C52H79N5O12 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 42-(2-Tetrazolyl)rapamycin


42-(2-Tetrazolyl)rapamycin is a prodrug compound of a rapamycin analog extracted from patent US 20080171763 A1, Example 1. Rapamycin is a specific mTOR inhibitor.

 Names

Name 42-(2-Tetrazolyl)rapamycin

 42-(2-Tetrazolyl)rapamycin Biological Activity

Description 42-(2-Tetrazolyl)rapamycin is a prodrug compound of a rapamycin analog extracted from patent US 20080171763 A1, Example 1. Rapamycin is a specific mTOR inhibitor.
Related Catalog
References

[1]. Karl W. Mollison, et al. Compounds and methods for treatment and prevention of diseases. US 20080171763 A1.

[2]. Ballou LM, et al. Rapamycin and mTOR kinase inhibitors. J Chem Biol. 2008 Nov;1(1-4):27-36.

 Chemical & Physical Properties

Molecular Formula C52H79N5O12
Molecular Weight 966.21
InChIKey IURNHYDSJVLLPN-JUKNQOCSSA-N
SMILES COC1CC2CCC(C)C(O)(O2)C(=O)C(=O)N2CCCCC2C(=O)OC(C(C)CC2CCC(n3ncnn3)C(OC)C2)CC(=O)C(C)C=C(C)C(O)C(OC)C(=O)C(C)CC(C)C=CC=CC=C1C
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