CDK12-IN-3
Modify Date: 2024-02-18 17:26:37
CDK12-IN-3 structure
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Common Name | CDK12-IN-3 | ||
|---|---|---|---|---|
| CAS Number | 2220184-50-7 | Molecular Weight | 470.52 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H28F2N8O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CDK12-IN-3CMPD 7 is a potent and selective CDK12 inhibitor with an IC50 of 491 nM in enzymatic assay. |
| Name | CMPD 7 |
|---|
| Description | CMPD 7 is a potent and selective CDK12 inhibitor with an IC50 of 491 nM in enzymatic assay. |
|---|---|
| Related Catalog | |
| Target |
IC50: 491 nM (CDK12)[1] |
| In Vitro | CMPD 7 is a highly selective CDK12 inhibitor profiled across a panel of 352 kinases at 0.1 µM. CMPD 7 shows potent inhibition of phosphorylation of Ser2 on the CTD repeat domain of RNA Pol II as well as growth inhibition of OV90 cells and acute cytotoxicity to THP1 cells[1]. |
| References |
| Molecular Formula | C23H28F2N8O |
|---|---|
| Molecular Weight | 470.52 |