Compound 621433144
Modify Date: 2025-09-12 17:03:40
Compound 621433144 structure
|
Common Name | Compound 621433144 | ||
|---|---|---|---|---|
| CAS Number | 2223169-38-6 | Molecular Weight | 301.434 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H27N3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Compound 621433144Compound 621433144 (ZINC000621433144, Z3269026405) is a potent, selective full agonist of the D4 receptor with 2,500-fold subtype selectivity; Compound 621433144 was also functionally selective, with a 17-fold bias towards Gi signalling versus β-arrestin recruitment, compared to the characteristic agonist quinpirole. |
| Name | Compound 621433144 |
|---|
| Description | Compound 621433144 (ZINC000621433144, Z3269026405) is a potent, selective full agonist of the D4 receptor with 2,500-fold subtype selectivity; Compound 621433144 was also functionally selective, with a 17-fold bias towards Gi signalling versus β-arrestin recruitment, compared to the characteristic agonist quinpirole. |
|---|---|
| References | References 1. Lyu J, et al. Nature. 2019 Feb 6. doi: 10.1038/s41586-019-0917-9. View Related Products by Target Dopamine Receptor |
| Molecular Formula | C18H27N3O |
|---|---|
| Molecular Weight | 301.434 |