TLR9-IN-1

Modify Date: 2025-08-26 10:38:49

TLR9-IN-1 Structure
TLR9-IN-1 structure
Common Name TLR9-IN-1
CAS Number 2226366-86-3 Molecular Weight 421.54
Density N/A Boiling Point N/A
Molecular Formula C23H31N7O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TLR9-IN-1


TLR9-IN-1 is a potent and selective TLR9 inhibitor with an IC50 value of 7 nM for human TLR9. TLR9-IN-1 can be used for researching diseases associated with undesirable immune response[1].

 Names

Name TLR9-IN-1

 TLR9-IN-1 Biological Activity

Description TLR9-IN-1 is a potent and selective TLR9 inhibitor with an IC50 value of 7 nM for human TLR9. TLR9-IN-1 can be used for researching diseases associated with undesirable immune response[1].
Related Catalog
Target

human TLR9:7 nM (IC50)

In Vitro TLR9-IN-1 (compound no.29) (0-10 μM; 24 h) exhibits moderately inhibitory activity against IL-1b with an IC50 of 1.61 μM in human monocytes (co-incubated with TLR8 agonist ORN8L, RNA oligonucleotide)[1].
References

[1]. Albert Frederick Candia, et al. Toll-like receptor antagonist compounds and methods of use. WO2018089695

 Chemical & Physical Properties

Molecular Formula C23H31N7O
Molecular Weight 421.54
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