TLR9-IN-1
Modify Date: 2025-08-26 10:38:49
TLR9-IN-1 structure
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Common Name | TLR9-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 2226366-86-3 | Molecular Weight | 421.54 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H31N7O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TLR9-IN-1TLR9-IN-1 is a potent and selective TLR9 inhibitor with an IC50 value of 7 nM for human TLR9. TLR9-IN-1 can be used for researching diseases associated with undesirable immune response[1]. |
| Name | TLR9-IN-1 |
|---|
| Description | TLR9-IN-1 is a potent and selective TLR9 inhibitor with an IC50 value of 7 nM for human TLR9. TLR9-IN-1 can be used for researching diseases associated with undesirable immune response[1]. |
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| Related Catalog | |
| Target |
human TLR9:7 nM (IC50) |
| In Vitro | TLR9-IN-1 (compound no.29) (0-10 μM; 24 h) exhibits moderately inhibitory activity against IL-1b with an IC50 of 1.61 μM in human monocytes (co-incubated with TLR8 agonist ORN8L, RNA oligonucleotide)[1]. |
| References |
| Molecular Formula | C23H31N7O |
|---|---|
| Molecular Weight | 421.54 |
| InChIKey | FRMXKWKQIYLSMO-UHFFFAOYSA-N |
| SMILES | Cc1ccc(-n2cc3cnnc(N4CCC(C(=O)NCCCN(C)C)CC4)c3n2)cc1 |