FM-381
Modify Date: 2024-01-18 19:58:17
FM-381 structure
|
Common Name | FM-381 | ||
|---|---|---|---|---|
| CAS Number | 2226521-65-7 | Molecular Weight | 428.486 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 749.8±70.0 °C at 760 mmHg | |
| Molecular Formula | C24H24N6O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 407.3±35.7 °C | |
Use of FM-381FM-381 is a JAK3 specific reversible covalent inhibitor with IC50 of 127 pM for JAK3 and demonstrates 400-, 2,700- and 3,600-fold selectivity over JAK1, JAK2, and TYK2, respectively. |
| Name | FM-381 |
|---|---|
| Synonym | More Synonyms |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 749.8±70.0 °C at 760 mmHg |
| Molecular Formula | C24H24N6O2 |
| Molecular Weight | 428.486 |
| Flash Point | 407.3±35.7 °C |
| Exact Mass | 428.196075 |
| LogP | 3.77 |
| Appearance of Characters | powder.white to beige |
| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
| Index of Refraction | 1.709 |
| Storage condition | 2-8°C |
| (2E)-2-Cyano-3-[5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)-2-furyl]-N,N-dimethylacrylamide |
| (E)-2-Cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)furan-2-yl)-N,N-dimethylacrylamide |
| 2-Cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)furan-2-yl)-N,N-dimethylacrylamide |
| 2-Propenamide, 2-cyano-3-[5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-b]pyridin-2-yl)-2-furanyl]-N,N-dimethyl-, (2E)- |
| MFCD31630713 |