(S,R,S)-AHPC-Me-C5-COOH

Modify Date: 2024-01-14 14:38:35

(S,R,S)-AHPC-Me-C5-COOH Structure
(S,R,S)-AHPC-Me-C5-COOH structure
Common Name (S,R,S)-AHPC-Me-C5-COOH
CAS Number 2229976-21-8 Molecular Weight 586.74
Density N/A Boiling Point N/A
Molecular Formula C30H42N4O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S,R,S)-AHPC-Me-C5-COOH


(S,R,S)-AHPC-Me-C5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C5-COOH can be used in PROTAC DT2216 (HY-130604)[1].

 Names

Name (S,R,S)-AHPC-Me-C5-COOH

 (S,R,S)-AHPC-Me-C5-COOH Biological Activity

Description (S,R,S)-AHPC-Me-C5-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the a VHL ligand and a linker. (S,R,S)-AHPC-Me-C5-COOH can be used in PROTAC DT2216 (HY-130604)[1].
Related Catalog
Target

VHL

In Vitro DT2216 is a selective B-cell lymphoma extra large (BCL-XL) PROTAC degrader[1].
References

[1]. Khan S, et al. A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nat Med. 2019 Dec;25(12):1938-1947.

 Chemical & Physical Properties

Molecular Formula C30H42N4O6S
Molecular Weight 586.74

 Safety Information

Hazard Codes Xi