1,3-bis(tosyloxy)-2,2-dimethylpropane

Modify Date: 2024-01-12 16:39:26

1,3-bis(tosyloxy)-2,2-dimethylpropane Structure
1,3-bis(tosyloxy)-2,2-dimethylpropane structure
Common Name 1,3-bis(tosyloxy)-2,2-dimethylpropane
CAS Number 22308-12-9 Molecular Weight 412.52000
Density 1.254g/cm3 Boiling Point 568.9ºC at 760mmHg
Molecular Formula C19H24O6S2 Melting Point 119.0 to 123.0 °C
MSDS N/A Flash Point 297.9ºC

 Use of 1,3-bis(tosyloxy)-2,2-dimethylpropane




 Names

Name [2,2-dimethyl-3-(4-methylphenyl)sulfonyloxypropyl] 4-methylbenzenesulfonate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.254g/cm3
Boiling Point 568.9ºC at 760mmHg
Melting Point 119.0 to 123.0 °C
Molecular Formula C19H24O6S2
Molecular Weight 412.52000
Flash Point 297.9ºC
Exact Mass 412.10100
PSA 103.50000
LogP 5.60200
Vapour Pressure 2.27E-12mmHg at 25°C
Index of Refraction 1.551

 MSDS


Section I.Chemical Product and Company Identification
Chemical Name 1,3-Bis(tosyloxy)-2,2-dimethylpropane
Portland OR
Synonym1,3-Propanediol, 2,2-dimethyl-, 1,3-bis(4-methylbenzene
sulfonate) (CA INDEX NAME);
1,3-Bis(p-toluenesulfonyloxy)-2,2-dimethylpropane;
2,2-Dimethyl-1,3-propanediol Ditosylate;
Neopentyl Glycol Ditosylate
Chemical FormulaC19H24O6S2
CAS Number22308-12-9

Section II.Composition and Information on Ingredients
Chemical NameCAS Number Percent (%)TLV/PELToxicology Data
1,3-Bis(tosyloxy)-2,2-dimethylpropane22308-12-9 Min. 98.0 (GC) Not available.Not available.

Section III. Hazards Identification
No specific information is available in our data base regarding the toxic effects of this material for humans. However,
Acute Health Effects
exposure to any chemical should be kept to a minimum. Skin and eye contact may result in irritation. May be harmful if
inhaled or ingested. Always follow safe industrial hygiene practices and wear proper protective equipment when handling
this compound. Follow safe industrial hygiene practices and always wear proper protective equipment when handling this
compound.
CARCINOGENIC EFFECTS : Not available.
Chronic Health Effects
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
DEVELOPMENTAL TOXICITY: Not available.
Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions.

Section IV.First Aid Measures
Eye ContactCheck for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15
minutes. Get medical attention.
Skin ContactIn case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing
before reuse. Thoroughly clean shoes before reuse. Get medical attention.
InhalationIf the victim is not breathing, perform mouth-to-mouth resuscitation. Loosen tight clothing such as a collar, tie, belt or
waistband. If breathing is difficult, oxygen can be administered. Seek medical attention if respiration problems do not
improve.
INDUCE VOMITING by sticking finger in throat. Lower the head so that the vomit will not reenter the mouth and throat.
Ingestion
Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not breathing, perform mouth-to-mouth
resuscitation. Examine the lips and mouth to ascertain whether the tissues are damaged, a possible indication that the toxic
material was ingested; the absence of such signs, however, is not conclusive. SEEK IMMEDIATE MEDICAL ATTENTION in
case of ingestion of a radioactive material.

Section V.Fire and Explosion Data
Not available.
May be combustible at high temperature.Auto-Ignition
Flammability
Flash PointsFlammable LimitsNot available.
Not available.
Combustion ProductsThese products are toxic carbon oxides (CO, CO2), sulfur oxides (SO2, SO3...).
Fire Hazards
Not available.
Risks of explosion of the product in presence of mechanical impact: Not available.
Explosion Hazards
Risks of explosion of the product in presence of static discharge: Not available.
Fire Fighting MediaSMALL FIRE: Use DRY chemical powder.
and InstructionsLARGE FIRE: Use water spray, fog or foam. DO NOT use water jet.
Consult with local fire authorities before attempting large scale fire-fighting operations.
Continued on Next Page
1,3-Bis(tosyloxy)-2,2-dimethylpropane

Section VI.Accidental Release Measures
Spill CleanupUse a shovel to put the material into a convenient waste disposal container. Finish cleaning the spill by rinsing any
contaminated surfaces with copious amounts of water. Consult federal, state, and/or local authorities for assistance on
Instructions
disposal.

Section VII. Handling and Storage
Handling and StorageKeep away from heat. Mechanical exhaust required. When not in use, tightly seal the container and store in a dry, cool
place. Avoid excessive heat and light. Do not breathe dust.
Information

Section VIII. Exposure Controls/Personal Protection
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended
Engineering Controls
exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants
below the exposure limit.
Splash goggles. Lab coat. Dust respirator. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a
Personal Protection
specialist BEFORE handling this product. Be sure to use a MSHA/NIOSH approved respirator or equivalent.
Exposure LimitsNot available.

Section IX. Physical and Chemical Properties
Physical state @ 20°CSolid. (White crystal lumps)Solubility
Not available.
Not available.
Specific Gravity
Molecular Weight412.52Partition CoefficientNot available.
Boiling PointNot available.Vapor PressureNot applicable.
121°C (249.8°F)Not available.
Melting PointVapor Density
Refractive IndexNot available.VolatilityNot available.
Not available.Not available.
Critical TemperatureOdor
Not available.Not available.
ViscosityTaste

Section X.Stability and Reactivity Data

This material is stable if stored under proper conditions. (See Section VII for instructions)
Stability
Conditions of InstabilityNot available.
Incompatibilities
Reactive with oxidizing agents.

Section XI. Toxicological Information
Not available.
RTECS Number
Eye Contact. Ingestion. inhalation.
Routes of Exposure
Not available.
Toxicity Data
Chronic Toxic EffectsCARCINOGENIC EFFECTS : Not available.
MUTAGENIC EFFECTS : Not available.
TERATOGENIC EFFECTS : Not available.
DEVELOPMENTAL TOXICITY: Not available.
Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions.
No specific information is available in our data base regarding the toxic effects of this material for humans. However,
Acute Toxic Effects
exposure to any chemical should be kept to a minimum. Skin and eye contact may result in irritation. May be harmful if
inhaled or ingested. Always follow safe industrial hygiene practices and wear proper protective equipment when handling this
compound. Follow safe industrial hygiene practices and always wear proper protective equipment when handling this
compound.

Section XII.Ecological Information
Not available.
Ecotoxicity
Environmental FateNot available.
Continued on Next Page
1,3-Bis(tosyloxy)-2,2-dimethylpropane

Section XIII. Disposal Considerations
Waste DisposalRecycle to process, if possible. Consult your local regional authorities. You may be able to dissove or mix material with a
combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all
federal, state and locl regulations when disposing of the substance.

Section XIV. Transport Information
Not a DOT controlled material (United States).
DOT Classification
PIN NumberNot applicable.
Proper Shipping NameNot applicable.
Packing Group (PG)Not applicable.
DOT Pictograms

Section XV. Other Regulatory Information and Pictograms
TSCA Chemical InventoryThis product is NOT on the EPA Toxic Substances Control Act (TSCA) inventory. The following notices are required by 40
CFR 720.36 (C) for those products not on the inventory list:
(EPA)
(i) These products are supplied solely for use in research and development by or under the supervision of a technically
qualified individual as defined in 40 CFR 720.0 et sec.
(ii) The health risks of these products have not been fully determined. Any information that is or becomes available will be
supplied on an MSDS sheet.
WHMIS Classificationnot available
(Canada)
EINECS Number (EEC)Not available.
EEC Risk Statementsnot available


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes Xn
Safety Phrases S22-S24/25
HS Code 2905199090

 Synthetic Route

~99%

1,3-bis(tosyloxy)-2,2-dimethylpropane Structure

1,3-bis(tosylox...

CAS#:22308-12-9

Literature: Gobbi, Luca Claudio; Gubler, Marcel; Neidhart, Werner; Nettekoven, Matthias Heinrich Patent: US2005/113374 A1, 2005 ; Location in patent: Page/Page column 7; 14-15 ;

~%

1,3-bis(tosyloxy)-2,2-dimethylpropane Structure

1,3-bis(tosylox...

CAS#:22308-12-9

Literature: Chemische Berichte, , vol. 114, # 4 p. 1551 - 1553

 Preparation


 Customs

HS Code 2905199090
Summary 2905199090. saturated monohydric alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

 Synonyms

Neopentyl Glycol Ditosylate
2,2-Dimethyl-1,3-propanediol Ditosylate
ditosylate of 2,2-dimethyl-1,3-propanediol
MFCD00110766
1,3-Bis(tosyloxy)-2,2-diMethylpropane
1,3-Bis(p-toluenesulfonyloxy)-2,2-dimethylpropane
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