methyl 1-chloro-4-hydroxyisoquinoline-3-carboxylate

Modify Date: 2024-01-11 22:00:00

methyl 1-chloro-4-hydroxyisoquinoline-3-carboxylate Structure
methyl 1-chloro-4-hydroxyisoquinoline-3-carboxylate structure
Common Name methyl 1-chloro-4-hydroxyisoquinoline-3-carboxylate
CAS Number 223388-20-3 Molecular Weight 237.63900
Density N/A Boiling Point N/A
Molecular Formula C11H8ClNO3 Melting Point 164-168ºC
MSDS Chinese USA Flash Point N/A
Symbol GHS05
GHS05
Signal Word Danger

 Names

Name methyl 1-chloro-4-hydroxyisoquinoline-3-carboxylate

 Chemical & Physical Properties

Melting Point 164-168ºC
Molecular Formula C11H8ClNO3
Molecular Weight 237.63900
Exact Mass 237.01900
PSA 59.42000
LogP 2.38040

 Safety Information

Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H318
Precautionary Statements P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 41
Safety Phrases 26-39
RIDADR NONH for all modes of transport
HS Code 2933499090

 Synthetic Route

~95%

methyl 1-chloro-4-hydroxyisoquinoline-3-carboxylate Structure

methyl 1-chloro...

CAS#:223388-20-3

Literature: Roche Palo Alto LLC Patent: US2006/252785 A1, 2006 ; Location in patent: Page/Page column 18; 30 ; US 20060252785 A1

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methyl 1-chloro-4-hydroxyisoquinoline-3-carboxylate Structure

methyl 1-chloro...

CAS#:223388-20-3

Literature: Hendricks, Robert T.; Spencer, Stacey R.; Blake, James F.; Fell, Jay B.; Fischer, John P.; Stengel, Peter J.; Leveque, Vincent J.P.; LePogam, Sophie; Rajyaguru, Sonal; Najera, Isabel; Josey, John A.; Swallow, Steven Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 2 p. 410 - 414

 Precursor & DownStream

Precursor  1

DownStream  0

 Customs

HS Code 2933499090
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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