NLRP3-IN-19

Modify Date: 2024-07-08 17:01:35

NLRP3-IN-19 Structure
NLRP3-IN-19 structure
Common Name NLRP3-IN-19
CAS Number 2238819-65-1 Molecular Weight 402.47
Density N/A Boiling Point N/A
Molecular Formula C19H22N4O4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NLRP3-IN-19


JT001 (NLRP3-IN-19) is a potent, specific and orally active inhibitor of NLRP3. JT001 can inhibit NLRP3 inflammasome assembly, resulting in the inhibition of cytokine release and the prevention of pyroptosis. JT001 can be used for the research of nonalcoholic steatohepatitis and liver fibrosis[1].

 Names

Name NLRP3-IN-19

 NLRP3-IN-19 Biological Activity

Description JT001 (NLRP3-IN-19) is a potent, specific and orally active inhibitor of NLRP3. JT001 can inhibit NLRP3 inflammasome assembly, resulting in the inhibition of cytokine release and the prevention of pyroptosis. JT001 can be used for the research of nonalcoholic steatohepatitis and liver fibrosis[1].
Related Catalog
Target

NLRP3

References

[1]. Povero D, et, al. Domain-Containing Protein 3 (NLRP3) Inflammasome that Attenuates Development of Nonalcoholic Steatohepatitis and Liver Fibrosis. J Pharmacol Exp Ther. 2023 Aug;386(2):242-258.  

 Chemical & Physical Properties

Molecular Formula C19H22N4O4S
Molecular Weight 402.47