Gymnemagenin

Modify Date: 2024-01-04 16:24:18

Gymnemagenin Structure
Gymnemagenin structure
Common Name Gymnemagenin
CAS Number 22467-07-8 Molecular Weight 506.714
Density 1.2±0.1 g/cm3 Boiling Point 634.5±55.0 °C at 760 mmHg
Molecular Formula C30H50O6 Melting Point 330-331℃
MSDS USA Flash Point 262.0±26.1 °C

 Use of Gymnemagenin


Gymnemagenin is a triterpenoid isolated from G. sylvestre. Gymnemagenin is an agent for diabetes and obesity and also possesses antiviral properties[1][2].

 Names

Name protoaescigenin
Synonym More Synonyms

 Gymnemagenin Biological Activity

Description Gymnemagenin is a triterpenoid isolated from G. sylvestre. Gymnemagenin is an agent for diabetes and obesity and also possesses antiviral properties[1][2].
Related Catalog
In Vivo Gymnemagenin has a poor oral bioavailability (~ 14 %) in rats[2]. Gymnemagenin has a short half-life and a high clearance in rats[2]. Gymnemagenin metabolizes rapidly with a short apparent and intrinsic half-life (~ 7 min) and high intrinsic clearance[2].
References

[1]. Parthasarathy R, et al. Gymnemagenin-producing endophytic fungus isolated from a medicinal plant Gymnema sylvestre R.Br. Appl Biochem Biotechnol. 2014 Mar;172(6):3141-52.

[2]. In Vitro Metabolic Stability and Permeability of Gymnemagenin and Its In Vivo Pharmacokinetic Correlation in Rats - A Pilot Study.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 634.5±55.0 °C at 760 mmHg
Melting Point 330-331℃
Molecular Formula C30H50O6
Molecular Weight 506.714
Flash Point 262.0±26.1 °C
Exact Mass 506.360748
PSA 121.38000
LogP 3.98
Vapour Pressure 0.0±4.2 mmHg at 25°C
Index of Refraction 1.598

 Safety Information

RIDADR NONH for all modes of transport

 Synonyms

Protoaescigenin
Olean-12-ene-3,16,21,22,23,28-hexol, (3β,16β,21β,22α)-
(3β,16β,21β,22α)-Olean-12-ene-3,16,21,22,23,28-hexol
Gymnemagenin