5-(trifluoromethyl)-1H-indazol-3-amine

Modify Date: 2024-01-09 21:12:10

5-(trifluoromethyl)-1H-indazol-3-amine Structure
5-(trifluoromethyl)-1H-indazol-3-amine structure
Common Name 5-(trifluoromethyl)-1H-indazol-3-amine
CAS Number 2250-53-5 Molecular Weight 201.14900
Density 1.536g/cm3 Boiling Point 358.5ºC at 760mmHg
Molecular Formula C8H6F3N3 Melting Point 114-118 °C
MSDS USA Flash Point 170.6ºC

 Names

Name 5-(trifluoromethyl)-1H-indazol-3-amine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.536g/cm3
Boiling Point 358.5ºC at 760mmHg
Melting Point 114-118 °C
Molecular Formula C8H6F3N3
Molecular Weight 201.14900
Flash Point 170.6ºC
Exact Mass 201.05100
PSA 54.70000
LogP 2.74510
Vapour Pressure 2.53E-05mmHg at 25°C
Index of Refraction 1.617

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NK7772500
CHEMICAL NAME :
1H-Indazole, 3-amino-5-(trifluoromethyl)-
CAS REGISTRY NUMBER :
2250-53-5
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H6-F3-N3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
90 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 54,275,1983

 Safety Information

Hazard Codes Xi
HS Code 2933990090

 Synthetic Route

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5-(trifluoromethyl)-1H-indazol-3-amine Structure

5-(trifluoromet...

CAS#:2250-53-5

Literature: Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 23 p. 5293 - 5297

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5-(trifluoromethyl)-1H-indazol-3-amine Structure

5-(trifluoromet...

CAS#:2250-53-5

Literature: US2011/306592 A1, ; Page/Page column 93 ;

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

5-(trifluoromethyl)-1H-indazole-3-ylamine
BAY h 1127
3-Amino-5-trifluormethylindazol
3-Amino-5-(trifluoromethyl)-1H-indazole
5-(trifluoromethyl)-1H-indazole-3-amine
5-trifluoromethyl-1H-indazol-3-ylamine
3-amino-5-trifluoromethylindazole
1H-Indazole,3-amino-5-(trifluoromethyl)
5-trifluoromethyl-1(2)H-indazol-3-ylamine
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