Dooku 1
Modify Date: 2025-08-25 17:44:36
Dooku 1 structure
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Common Name | Dooku 1 | ||
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| CAS Number | 2253744-54-4 | Molecular Weight | 326.20 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C13H9Cl2N3OS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Dooku 1Dooku1, an analog of Yoda1, is a selective antagonist of the endogenous Piezo1 channel. Dooku1 inhibited 2 μM Yoda1-induced Ca2+-entry with IC50 values of 1.3 μM (in HEK 293 cells) and 1.5 μM (in HUVECs). Dooku1 inhibits Yoda1-induced relaxation of aorta[1]. |
| Name | Dooku1 |
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| Synonym | More Synonyms |
| Description | Dooku1, an analog of Yoda1, is a selective antagonist of the endogenous Piezo1 channel. Dooku1 inhibited 2 μM Yoda1-induced Ca2+-entry with IC50 values of 1.3 μM (in HEK 293 cells) and 1.5 μM (in HUVECs). Dooku1 inhibits Yoda1-induced relaxation of aorta[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C13H9Cl2N3OS |
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| Molecular Weight | 326.20 |
| InChIKey | MNPOBXLPCWFONX-UHFFFAOYSA-N |
| SMILES | Clc1cccc(Cl)c1CSc1nnc(-c2ccc[nH]2)o1 |
| Hazard Codes | Xi |
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| MFCD32174346 |