(S)-Higenamine

Modify Date: 2024-01-08 18:53:41

(S)-Higenamine Structure
(S)-Higenamine structure
Common Name (S)-Higenamine
CAS Number 22672-77-1 Molecular Weight 271.31100
Density N/A Boiling Point N/A
Molecular Formula C16H17NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (S)-Higenamine


(S)-Higenamine ((S)-Norcoclaurine) is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS)[1].

 Names

Name (S)-norcoclaurine

 (S)-Higenamine Biological Activity

Description (S)-Higenamine ((S)-Norcoclaurine) is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS)[1].
Related Catalog
In Vitro The biosynthetic pathway leading to benzylisoquinoline alkaloids originates from the enzyme-catalyzed condensation of dopamine and 4-hydrophenylacetaldehyde to yield (S)-norcoclaurine. Both substrates are secondary metabolites derived from the decarboxylation/hydroxylation/deamination of tyrosine[1].
References

[1]. Minami H, et al. Functional analysis of norcoclaurine synthase in Coptis japonica. J Biol Chem. 2007;282(9):6274‐6282.

 Chemical & Physical Properties

Molecular Formula C16H17NO3
Molecular Weight 271.31100
Exact Mass 271.12100
PSA 72.72000
LogP 2.56170
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