Isoallolithocholic acid

Modify Date: 2025-08-25 20:14:04

Isoallolithocholic acid Structure
Isoallolithocholic acid structure
 Common Name Isoallolithocholic acid
CAS Number 2276-93-9 Molecular Weight 376.57300
Density 1.073g/cm3 Boiling Point 511ºC at 760mmHg
Molecular Formula C24H40O3 Melting Point N/A
MSDS N/A Flash Point 276.9ºC

 Use of Isoallolithocholic acid


Alloisolithocholic acid (AILCA) activates large-conductance calcium-activated potassium (BK) channels with an EC50 value of 44.21 μM in Xenopus oocytes[1].

 Names

Name (4R)-4-[(3S,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid
Synonym More Synonyms

 Isoallolithocholic acid Biological Activity

Description Alloisolithocholic acid (AILCA) activates large-conductance calcium-activated potassium (BK) channels with an EC50 value of 44.21 μM in Xenopus oocytes[1].
Related Catalog
References

[1]. Bukiya AN, et al. Structural determinants of monohydroxylated bile acids to activate beta 1 subunit-containing BK channels. J Lipid Res. 2008 Nov;49(11):2441-51.

 Chemical & Physical Properties

Density 1.073g/cm3
Boiling Point 511ºC at 760mmHg
Molecular Formula C24H40O3
Molecular Weight 376.57300
Flash Point 276.9ºC
Exact Mass 376.29800
PSA 57.53000
LogP 5.50710
Vapour Pressure 1.4E-12mmHg at 25°C
Index of Refraction 1.528

 Synonyms

lithocholic acid
Isoallolithocholate
3b-Hydroxy-5a-cholanate
Isoallolithocholic acid
3b-Hydroxy-5a-cholanoate
Alloisolithocholic acid
3b-hydroxy-5a-cholan-24-oic acid
Isolithocholic acid
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