MK-0429
Modify Date: 2024-01-05 14:34:24
MK-0429 structure
|
Common Name | MK-0429 | ||
|---|---|---|---|---|
| CAS Number | 227963-15-7 | Molecular Weight | 439.508 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 699.0±55.0 °C at 760 mmHg | |
| Molecular Formula | C23H29N5O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 376.5±31.5 °C | |
Use of MK-0429MK-0429 is a potent integrin antagonist with IC50s of 12.2 nM (α5β1 integrin) and 2.8 nM (αvβ3 integrin), respectively. |
| Name | MK-0429 |
|---|---|
| Synonym | More Synonyms |
| Description | MK-0429 is a potent integrin antagonist with IC50s of 12.2 nM (α5β1 integrin) and 2.8 nM (αvβ3 integrin), respectively. |
|---|---|
| Related Catalog | |
| Target |
IC50: 12.2 nM (α5β1 integrin), 2.8 nM (αvβ3 integrin), 1.6 nM (αvβ1 integrin), 0.7 nM (αvβ6 integrin), 0.5 nM (αvβ8 integrin), 0.1 nM (αvβ5 integrin)[1]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 699.0±55.0 °C at 760 mmHg |
| Molecular Formula | C23H29N5O4 |
| Molecular Weight | 439.508 |
| Flash Point | 376.5±31.5 °C |
| Exact Mass | 439.221954 |
| LogP | 2.90 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
| Index of Refraction | 1.606 |
| (3S)-3-(6-methoxypyridin-3-yl)-3-{2-oxo-3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]imidazolidin-1-yl}propanoic acid |
| 1JL033A2D0 |
| MK-0429 |
| 3-Pyridinepropanoic acid, 6-methoxy-β-[2-oxo-3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1-imidazolidinyl]-, (βS)- |
| (3S)-3-(6-Methoxy-3-pyridinyl)-3-{2-oxo-3-[3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)propyl]-1-imidazolidinyl}propanoic acid |