CR 665
Modify Date: 2025-08-22 12:26:01
CR 665 structure
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Common Name | CR 665 | ||
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| CAS Number | 228546-92-7 | Molecular Weight | 671.83200 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C36H49N9O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CR 665CR 665 (JNJ 38488502) is a peripherally selective κ-opioid agonist. CR 665 can activate the kappa opioid receptor with EC50 value of 10.9 nM. CR 665 can be used for the research of peripheral pain[1][2]. |
| Name | (2R)-2-[[(2R)-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-N-[(2R)-5-(diaminomethylideneamino)-1-oxo-1-(pyridin-4-ylmethylamino)pentan-2-yl]hexanamide |
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| Synonym | More Synonyms |
| Description | CR 665 (JNJ 38488502) is a peripherally selective κ-opioid agonist. CR 665 can activate the kappa opioid receptor with EC50 value of 10.9 nM. CR 665 can be used for the research of peripheral pain[1][2]. |
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| Related Catalog | |
| Target |
C50: 10.9 nM (κ-opioid)[1] |
| In Vitro | CR 665 exhibits high peripheral to central nervous system (CNS) selectivity[1]. CR 665 can activate the kappa opioid receptor with EC50 value of 10.9 nM[1]. |
| Molecular Formula | C36H49N9O4 |
|---|---|
| Molecular Weight | 671.83200 |
| Exact Mass | 671.39100 |
| PSA | 231.17000 |
| LogP | 6.67080 |
| UNII-3BX9UG06GG |
| D-Argininamide,D-phenylalanyl-D-phenylalanyl-D-norleucyl-N-(4-pyridinylmethyl) |
| CR665 |