PROTAC ERRα ligand 2

Modify Date: 2024-01-11 16:23:27

PROTAC ERRα ligand 2 Structure
PROTAC ERRα ligand 2 structure
Common Name PROTAC ERRα ligand 2
CAS Number 2306388-57-6 Molecular Weight 445.31
Density N/A Boiling Point N/A
Molecular Formula C20H13F6NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PROTAC ERRα ligand 2


PROTAC ERRα ligand 2 is an estrogen-related receptor α (ERRα) inverse agonist with an IC50 of 5.67 nM. PROTAC ERRα ligand 2 (IC50=5.67 nM) displays a ~11-fold improved potency than XCT790 (IC50=61.3 nM)[1].

 Names

Name PROTAC ERRα ligand 2

 PROTAC ERRα ligand 2 Biological Activity

Description PROTAC ERRα ligand 2 is an estrogen-related receptor α (ERRα) inverse agonist with an IC50 of 5.67 nM. PROTAC ERRα ligand 2 (IC50=5.67 nM) displays a ~11-fold improved potency than XCT790 (IC50=61.3 nM)[1].
Related Catalog
References

[1]. Peng L, et al. Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation. ACS Med Chem Lett. 2019 Apr 12;10(5):767-772.

 Chemical & Physical Properties

Molecular Formula C20H13F6NO4
Molecular Weight 445.31
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