MeOIstPyrd

Modify Date: 2024-01-04 15:35:17

MeOIstPyrd Structure
MeOIstPyrd structure
 Common Name MeOIstPyrd
CAS Number 2308548-54-9 Molecular Weight 304.37
Density N/A Boiling Point N/A
Molecular Formula C14H16N4O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MeOIstPyrd


MeOIstPyrd is an anti-skin cancer agent. MeOIstPyrd inhibits cell proliferation, migration, and spheroid formation by activating the mitochondrial intrinsic apoptotic pathway. MeOIstPyrd induces DNA damage. MeOIstPyrd activates p53, and increases the half-life of p53 and stabilizes p53 by phosphorylating it at ser15. MeOIstPyrd binds to MDM2 in the p53 sub-pocket and blocks p53-MDM2 interaction[1].

 Names

Name MeOIstPyrd

 MeOIstPyrd Biological Activity

Description MeOIstPyrd is an anti-skin cancer agent. MeOIstPyrd inhibits cell proliferation, migration, and spheroid formation by activating the mitochondrial intrinsic apoptotic pathway. MeOIstPyrd induces DNA damage. MeOIstPyrd activates p53, and increases the half-life of p53 and stabilizes p53 by phosphorylating it at ser15. MeOIstPyrd binds to MDM2 in the p53 sub-pocket and blocks p53-MDM2 interaction[1].
Related Catalog
References

[1]. Nerina Shahi, et al. 5-Methoxyisatin N(4)-Pyrrolidinyl Thiosemicarbazone (MeOIstPyrd) Restores Mutant p53 and Inhibits the Growth of Skin Cancer Cells, In Vitro. https://pubs.acs.org/doi/10.1021/acsomega.3c03824. ACS Omega 2023, 8, 35, 31998鈥?2016.

 Chemical & Physical Properties

Molecular Formula C14H16N4O2S
Molecular Weight 304.37
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Chemsrc provides MeOIstPyrd(CAS#:2308548-54-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of MeOIstPyrd are included as well.>> amp version: MeOIstPyrd

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