2(1H)-Pyridinone,4-hydroxy-1-(2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-

Modify Date: 2024-01-08 18:02:28

2(1H)-Pyridinone,4-hydroxy-1-(2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)- Structure
2(1H)-Pyridinone,4-hydroxy-1-(2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)- structure
Common Name 2(1H)-Pyridinone,4-hydroxy-1-(2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-
CAS Number 23220-74-8 Molecular Weight 555.53
Density 1.43g/cm3 Boiling Point 709.4ºC at 760mmHg
Molecular Formula C31H25NO9 Melting Point N/A
MSDS N/A Flash Point 382.8ºC

 Use of 2(1H)-Pyridinone,4-hydroxy-1-(2,3,5-tri-O-benzoyl-b-D-ribofuranosyl)-


4-Hydroxy-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyridinone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 3-Deaza-uridin-tribenzoat
Synonym More Synonyms

  Biological Activity

Description 4-Hydroxy-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyridinone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.43g/cm3
Boiling Point 709.4ºC at 760mmHg
Molecular Formula C31H25NO9
Molecular Weight 555.53
Flash Point 382.8ºC
Exact Mass 555.15300
PSA 130.36000
LogP 3.75950
Vapour Pressure 4.03E-21mmHg at 25°C
Index of Refraction 1.67

 Synonyms

3-hydroxypropyl 2-thienyl ketone
3-Deazauridin-2',3',5'-tribenzoat