1H,12H-Benzo[i]pyrano[3,4-g]indolizin-12-one,2,3,5,6,8,9,10,13-octahydro-2-methoxy-, (2S,13bS)- structure
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Common Name | 1H,12H-Benzo[i]pyrano[3,4-g]indolizin-12-one,2,3,5,6,8,9,10,13-octahydro-2-methoxy-, (2S,13bS)- | ||
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CAS Number | 23255-54-1 | Molecular Weight | 275.34300 | |
Density | 1.25g/cm3 | Boiling Point | 486.6ºC at 760 mmHg | |
Molecular Formula | C16H21NO3 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 248.1ºC |
Use of 1H,12H-Benzo[i]pyrano[3,4-g]indolizin-12-one,2,3,5,6,8,9,10,13-octahydro-2-methoxy-, (2S,13bS)-Dihydro-β-erythroidine is a a competitive nicotinic receptor antagonist. Dihydro-β-erythroidine blocks the discriminative stimulus properties of nicotine. Dihydro-β-erythroidine inhibits the anxiolytic effect of nicotine induced[1][2]. |
Name | dihydro-β-erythroidine |
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Synonym | More Synonyms |
Description | Dihydro-β-erythroidine is a a competitive nicotinic receptor antagonist. Dihydro-β-erythroidine blocks the discriminative stimulus properties of nicotine. Dihydro-β-erythroidine inhibits the anxiolytic effect of nicotine induced[1][2]. |
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Related Catalog | |
In Vivo | Dihydro-β-erythroidine (0.5, 1.6, 5.0 mg/kg; s.c.) blocks the discriminative stimulus properties of nicotine in rats[1]. Dihydro-β-erythroidine (100 ng) shows antagonism of the anxiolytic effect of nicotine in the dorsal raphe´ nucleus in rats[2]. Animal Model: 200-250 g male hooded Lister rats[1] Dosage: 0.5, 1.6, 5.0 mg/kg Administration: S.c. Result: Prevented the development of CTAs (conditioned taste aversion) and blocked the discriminative stimulus effect of nicotine (0.2 or 0.4 mg/kg SC) for 45 min after its administration. |
References |
Density | 1.25g/cm3 |
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Boiling Point | 486.6ºC at 760 mmHg |
Molecular Formula | C16H21NO3 |
Molecular Weight | 275.34300 |
Flash Point | 248.1ºC |
Exact Mass | 275.15200 |
PSA | 38.77000 |
LogP | 1.75120 |
Vapour Pressure | 1.27E-09mmHg at 25°C |
Index of Refraction | 1.592 |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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dihydro-beta-erythroidine |
1-(2,6,6-trimethyl-1-cyclohexen-1-yl)butan-1-one |
.β.-Erythroidine, dihydro- |
1-(2,6,6-trimethylcyclohex-1-en-1-yl)butan-1-one |
(12S,13aS)-)-12-methoxy-1,4,5,6,9,11,12,13-octahydro-8H-pyrano[4',3':3,4]pyrido[2,1-i]indol-2-one |
1-Butyryl-2,6,6-trimethyl-cyclohexen |
(12S,13aS)-)-12-Methoxy-1,4,5,6,9,11,12,13-octahydro-8H-pyrano[4',3':3,4]pyrido[2,1-i]indol-2-on |