NS1219

Modify Date: 2024-04-07 14:07:32

NS1219 Structure
NS1219 structure
Common Name NS1219
CAS Number 233603-81-1 Molecular Weight 516.56700
Density N/A Boiling Point N/A
Molecular Formula C24H28N4O7S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NS1219


NS1219 ((R)-SPD502) is the isomer of NS 1209 HY-15074. NS1209 is a selective AMPA receptor antagonist with neuroprotective activity. NS1209 can be used for the research of stroke, neuropathic pain and epilepsy[1].

 Names

Name (R)-2-[5-(4-dimethylsulfamoyl-phenyl)-8-methyl-2-oxo-1,2,6,7,8,9- hexahydro-pyrrolo [3,2-h]isoquinolin-3-ylideneaminooxy]-4-hydroxy-butyric acid

 NS1219 Biological Activity

Description NS1219 ((R)-SPD502) is the isomer of NS 1209 HY-15074. NS1209 is a selective AMPA receptor antagonist with neuroprotective activity. NS1209 can be used for the research of stroke, neuropathic pain and epilepsy[1].
Related Catalog
References

[1]. Jan M Keppel Hesselink, et al. NS1209/SPD 502, A Novel Selective AMPA Antagonist for Stroke, Neuropathic Pain or Epilepsy? Drug Development Lessons Learned. Drug Dev Res. 2017 Mar;78(2):75-80.  

 Chemical & Physical Properties

Molecular Formula C24H28N4O7S
Molecular Weight 516.56700
Exact Mass 516.16800
PSA 157.22000
LogP 2.25690
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