Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride

Modify Date: 2024-09-16 18:52:50

Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride Structure
Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride structure
Common Name Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride
CAS Number 2341841-02-7 Molecular Weight 410.81
Density N/A Boiling Point N/A
Molecular Formula C17H19ClN4O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride


Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a linker. Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride can be used to design the PROTACs[1].

 Names

Name Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride

  Biological Activity

Description Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride incorporates a cereblon (CRBN) ligand for the E3 ubiquitin ligase, and a linker. Thalidomide 4'-oxyacetamide-alkyl-C2-amine hydrochloride can be used to design the PROTACs[1].
Related Catalog
Target

Cereblon

References

[1]. Zhou F, et al. Development of selective mono or dual PROTAC degrader probe of CDK isoforms. Eur J Med Chem. 2020;187:111952.

 Chemical & Physical Properties

Molecular Formula C17H19ClN4O6
Molecular Weight 410.81

 Safety Information

Hazard Codes Xi