EIDD-2801

Modify Date: 2024-01-16 17:08:45

EIDD-2801 Structure
EIDD-2801 structure
Common Name EIDD-2801
CAS Number 2349386-89-4 Molecular Weight 329.31
Density N/A Boiling Point N/A
Molecular Formula C13H19N3O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of EIDD-2801


EIDD-2801 is an orally bioavailable isopropylester prodrug of the ribonucleoside analog EIDD-1931. EIDD-2801 shows anti-influenza virus and coronaviruses activities. EIDD-2801 has the potential for seasonal and pandemic influenza treatment[1][2].

 Names

Name EIDD-2801
Synonym More Synonyms

 EIDD-2801 Biological Activity

Description EIDD-2801 is an orally bioavailable isopropylester prodrug of the ribonucleoside analog EIDD-1931. EIDD-2801 shows anti-influenza virus and coronaviruses activities. EIDD-2801 has the potential for seasonal and pandemic influenza treatment[1][2].
Related Catalog
In Vivo EIDD-2801 (7 mg/kg; oral; twice daily for 3.5 days) significantly reduces shed virus load and duration of fever[1]. Animal Model: Ca/09-infected female ferrets[1] Dosage: 7 mg/kg Administration: Oral; twice daily for 3.5 days Result: Shed virus load and duration of fever were significantly reduced.
References

[1]. Toots M, et al. Characterization of orally efficacious influenza drug with high resistance barrier in ferrets and human airway epithelia. Sci Transl Med. 2019 Oct 23;11(515). pii: eaax5866.

[2]. Timothy P. Sheahan, et al. An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 and multiple endemic, epidemic and bat coronavirus.

 Chemical & Physical Properties

Molecular Formula C13H19N3O7
Molecular Weight 329.31
Storage condition 2-8℃

 Synonyms

Molnupiravir