DBCO-PEG6-amine,DBCO-PEG6-NH2

Modify Date: 2024-01-09 17:48:47

DBCO-PEG6-amine,DBCO-PEG6-NH2 Structure
DBCO-PEG6-amine,DBCO-PEG6-NH2 structure
Common Name DBCO-PEG6-amine,DBCO-PEG6-NH2
CAS Number 2353409-98-8 Molecular Weight 611.73
Density 1.22±0.1 g/cm3(Predicted) Boiling Point 823.0±65.0 °C(Predicted)
Molecular Formula C33H45N3O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DBCO-PEG6-amine,DBCO-PEG6-NH2


DBCO-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name DBCO-PEG6-amine

 DBCO-PEG6-amine,DBCO-PEG6-NH2 Biological Activity

Description DBCO-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.22±0.1 g/cm3(Predicted)
Boiling Point 823.0±65.0 °C(Predicted)
Molecular Formula C33H45N3O8
Molecular Weight 611.73