PROTAC VEGFR-2 degrader-2

Modify Date: 2024-01-11 08:34:39

PROTAC VEGFR-2 degrader-2 structure	Common Name	PROTAC VEGFR-2 degrader-2
	CAS Number	2353417-85-1	Molecular Weight	930.10
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₀H₅₆FN₉O₆S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of PROTAC VEGFR-2 degrader-2

PROTAC VEGFR-2 degrader-2（PROTAC-4）, a PROTAC VEGFR-2 degrader, exhibits little VEGFR-2 inhibition (IC50> 1 μM) and anti-proliferative activity against EA.hy926 cells (IC50> 100μM)[1].

Name	PROTAC VEGFR-2 degrader-2

Description	PROTAC VEGFR-2 degrader-2（PROTAC-4）, a PROTAC VEGFR-2 degrader, exhibits little VEGFR-2 inhibition (IC50> 1 μM) and anti-proliferative activity against EA.hy926 cells (IC50> 100μM)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
References	[1]. Yuanyuan Shan, et al. Discovery of novel anti-angiogenesis agents. Part 11: Development of PROTACs based on active molecules with potency of promoting vascular normalization. Eur J Med Chem. 2020 Nov 1;205:112654.

Molecular Formula	C₅₀H₅₆FN₉O₆S
Molecular Weight	930.10