CDK7-IN-6

Modify Date: 2025-08-27 13:00:44

CDK7-IN-6 Structure
CDK7-IN-6 structure
Common Name CDK7-IN-6
CAS Number 2378710-04-2 Molecular Weight 524.06
Density N/A Boiling Point N/A
Molecular Formula C26H34ClN9O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CDK7-IN-6


CDK7-IN-6 is a potent and selective cyclin-dependent kinase (CDK7) inhibitor (IC50≤100 nM), extracted from patent WO2019197549 A1, compound 210. CDK7-IN-6 is > 200-fold selective for CDK7 over CDK1, CDK2, and CDK5. CDK7-IN-6 can be used for the research of cancer[1].

 Names

Name CDK7-IN-6

 CDK7-IN-6 Biological Activity

Description CDK7-IN-6 is a potent and selective cyclin-dependent kinase (CDK7) inhibitor (IC50≤100 nM), extracted from patent WO2019197549 A1, compound 210. CDK7-IN-6 is > 200-fold selective for CDK7 over CDK1, CDK2, and CDK5. CDK7-IN-6 can be used for the research of cancer[1].
Related Catalog
Target

CDK7:≤100 nM (IC50)

In Vitro CDK7-IN-6 inhibits the viability of HCT116, H460, MV4-11, A2780, and OVCAR cells (IC50≤1 μM)[1].
References

[1]. Kiyean NAM, et al.Preparation of pyrazolotriazine and/or pyrazolopyrimidine derivatives as selective inhibitor of cyclin dependent kinase. WO2019197549 A1.

 Chemical & Physical Properties

Molecular Formula C26H34ClN9O
Molecular Weight 524.06
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.