CDK7-IN-3
Modify Date: 2025-08-24 22:03:17
CDK7-IN-3 structure
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Common Name | CDK7-IN-3 | ||
|---|---|---|---|---|
| CAS Number | 2417302-07-7 | Molecular Weight | 490.46 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H26F3N6OP | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CDK7-IN-3CDK7-IN-3 is a selective CDK7 inhibitor with a KD of 0.059 nM. CDK7-IN-3 shows poor inhibition on CDK2 (Ki=390 nM), CDK9 (Ki=290 nM), CDK12 (Ki=78 nM). CDK7-IN-3 induce apoptosis in tumor cells and has antitumor activity. |
| Name | CDK7-IN-3 |
|---|
| Description | CDK7-IN-3 is a selective CDK7 inhibitor with a KD of 0.059 nM. CDK7-IN-3 shows poor inhibition on CDK2 (Ki=390 nM), CDK9 (Ki=290 nM), CDK12 (Ki=78 nM). CDK7-IN-3 induce apoptosis in tumor cells and has antitumor activity. |
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| Molecular Formula | C23H26F3N6OP |
|---|---|
| Molecular Weight | 490.46 |
| InChIKey | JDJOUBVVSQDIRC-AWEZNQCLSA-N |
| SMILES | CC1(C)CCC(Nc2ncc(C(F)(F)F)c(-c3c[nH]c4c(P(C)(C)=O)c(C#N)ccc34)n2)CN1 |