7,10-Dimethylbenzo[c]acridine

Modify Date: 2024-01-14 19:01:56

7,10-Dimethylbenzo[c]acridine Structure
7,10-Dimethylbenzo[c]acridine structure
Common Name 7,10-Dimethylbenzo[c]acridine
CAS Number 2381-40-0 Molecular Weight 257.329
Density 1.2±0.1 g/cm3 Boiling Point 470.2±14.0 °C at 760 mmHg
Molecular Formula C19H15N Melting Point 147-149ºC(lit.)
MSDS N/A Flash Point 209.8±12.7 °C

 Names

Name 7,10-dimethylbenzo[c]acridine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 470.2±14.0 °C at 760 mmHg
Melting Point 147-149ºC(lit.)
Molecular Formula C19H15N
Molecular Weight 257.329
Flash Point 209.8±12.7 °C
Exact Mass 257.120453
PSA 12.89000
LogP 5.55
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.738

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CU3485000
CHEMICAL NAME :
Benz(c)acridine, 7,10-dimethyl-
CAS REGISTRY NUMBER :
2381-40-0
BEILSTEIN REFERENCE NO. :
0192194
LAST UPDATED :
199710
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C19-H15-N
MOLECULAR WEIGHT :
257.35
WISWESSER LINE NOTATION :
T D6 B666 CNJ F J

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
190 mg/kg/16W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - chronic pulmonary edema Lungs, Thorax, or Respiration - bronchiolar constriction
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg/4W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
250 mg/kg/10D-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - hamster Kidney
DOSE/DURATION :
80 ug/L
REFERENCE :
BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 37,873,1978

 Safety Information

Hazard Codes Xn: Harmful;
Risk Phrases 20/21/22-36/37/38-40
Safety Phrases S22;S26;S36
WGK Germany 3
RTECS CU3485000
HS Code 2933990090

 Synthetic Route

~%

7,10-Dimethylbenzo[c]acridine Structure

7,10-Dimethylbe...

CAS#:2381-40-0

Literature: Pene et al. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1976 , p. 2277

 Precursor & DownStream

Precursor  1

DownStream  0

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

6,9-Dimethyl-1,2-benzacridine
7,10-Dimethyl-benzo<c>acridin
7,10-Dimethylbenzo[c]acridine
Benz[c]acridine, 7,10-dimethyl-
2,10-Dimethyl-7,8-benzoacridin
7,10-Dimethylbenz<c>acridin