α-Muricholic acid

Modify Date: 2024-01-03 13:02:59

α-Muricholic acid Structure
α-Muricholic acid structure
Common Name α-Muricholic acid
CAS Number 2393-58-0 Molecular Weight 408.57100
Density 1.184g/cm3 Boiling Point 565.7ºC at 760mmHg
Molecular Formula C24H40O5 Melting Point N/A
MSDS N/A Flash Point 310ºC

 Use of α-Muricholic acid


α-Muricholic acid is the most abundant primary bile acid in rodents[1][2].

 Names

Name (3α,5β,6β,7α)-3,6,7-Trihydroxycholan-24-oic acid
Synonym More Synonyms

 α-Muricholic acid Biological Activity

Description α-Muricholic acid is the most abundant primary bile acid in rodents[1][2].
Related Catalog
In Vivo Sulfated and non-sulfated bile acids are determined in the intestines and in the feces of 7-month-old germ-free and conventional male mice. The major bile acids from germ-free mice are cholic acid, α-Muricholic acid and β-Muricholic acid[1]. In the context of primary bile acid, α-Muricholic acid is greatly reduced in high-fat diet (HFD)-soybean protein isolate (SPI) mice compared to the HFD controls[2].
References

[1]. Eyssen HJ, et al. Sulfate bile acids in germ-free and conventional mice. Eur J Biochem. 1976 Jul 15;66(3):507-14.

[2]. Watanabe K, et al. Dietary soybean protein ameliorates high-fat diet-induced obesity by modifying the gut microbiota-dependent biotransformation of bile acids. PLoS One. 2018 Aug 13;13(8):e0202083.

 Chemical & Physical Properties

Density 1.184g/cm3
Boiling Point 565.7ºC at 760mmHg
Molecular Formula C24H40O5
Molecular Weight 408.57100
Flash Point 310ºC
Exact Mass 408.28800
PSA 97.99000
LogP 3.44870
Vapour Pressure 3.75E-15mmHg at 25°C
Index of Refraction 1.558

 Synonyms

Muricholic acid
α-Muricholic acid
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