MAO-B-IN-12

Modify Date: 2025-08-27 13:39:42

MAO-B-IN-12 Structure
MAO-B-IN-12 structure
Common Name MAO-B-IN-12
CAS Number 2394733-97-0 Molecular Weight 358.47
Density N/A Boiling Point N/A
Molecular Formula C22H30O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MAO-B-IN-12


MAO-B-IN-12 (Compound 16c) is a potent monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.3 μM. MAO-B-IN-12 shows a neuroprotective activity[1].

 Names

Name MAO-B-IN-12

 MAO-B-IN-12 Biological Activity

Description MAO-B-IN-12 (Compound 16c) is a potent monoamine oxidase B (MAO-B) inhibitor with an IC50 of 1.3 μM. MAO-B-IN-12 shows a neuroprotective activity[1].
Related Catalog
Target

MAO-B:1.3 μM (IC50)

References

[1]. Hitoshi Kamauchi, et al. Synthesis of natural product-like polyprenylated phenols and quinones: Evaluation of their neuroprotective activities. Bioorg Med Chem. 2020 Jan 1;28(1):115156.

 Chemical & Physical Properties

Molecular Formula C22H30O4
Molecular Weight 358.47

 MAO-B-IN-12Bioassay

View more

Name: Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect ce...
Source: ChEMBL
Target: Amine oxidase [flavin-containing] B
External Id: CHEMBL4610239
Name: Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect ce...
Source: ChEMBL
Target: Amine oxidase [flavin-containing] B
External Id: CHEMBL4610238
Name: Neuroprotective activity against H2O2-induced cytotoxicity in human SH-SY5Y cells ass...
Source: ChEMBL
Target: SH-SY5Y
External Id: CHEMBL4610241
Name: Neuroprotective activity against H2O2-induced cytotoxicity in human SH-SY5Y cells ass...
Source: ChEMBL
Target: SH-SY5Y
External Id: CHEMBL4610240
Name: Cytotoxicity against human SH-SY5Y cells assessed as effect on cell viability at 10 u...
Source: ChEMBL
Target: SH-SY5Y
External Id: CHEMBL4610243
Name: Mixed inhibition of recombinant human MAO-B expressed in baculovirus infected BTI ins...
Source: ChEMBL
Target: Amine oxidase [flavin-containing] B
External Id: CHEMBL4610246
Name: Tight-binding competitive inhibition of recombinant human MAO-B expressed in baculovi...
Source: ChEMBL
Target: Amine oxidase [flavin-containing] B
External Id: CHEMBL4610248
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