MAO-B-IN-12

• 常用名: MAO-B-IN-12
• 英文名: MAO-B-IN-12
• CAS号: 2394733-97-0
• 分子量: 358.47
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₂H₃₀O₄
• 熔点: N/A
• 闪点: N/A

MAO-B-IN-12用途

MAO-B-IN-12(化合物16c)是一种有效的单胺氧化酶B(MAO-B)抑制剂,IC50为1.3μM。MAO-B-IN-12具有神经保护活性[1]。

MAO-B-IN-12名称

• 英文名: MAO-B-IN-12

MAO-B-IN-12生物活性

• 描述: MAO-B-IN-12(化合物16c)是一种有效的单胺氧化酶B(MAO-B)抑制剂,IC50为1.3μM。MAO-B-IN-12具有神经保护活性[1]。
• 相关类别:
  信号通路 >> 神经信号通路 >> 单胺氧化酶
  研究领域 >> 神经疾病
• 靶点实验:

  MAO-B:1.3 μM (IC50)

• 参考文献:

  [1]. Hitoshi Kamauchi, et al. Synthesis of natural product-like polyprenylated phenols and quinones: Evaluation of their neuroprotective activities. Bioorg Med Chem. 2020 Jan 1;28(1):115156.

MAO-B-IN-12物理化学性质

• 分子式: C₂₂H₃₀O₄
• 分子量: 358.47

MAO-B-IN-12靶点实验

查看更多实验

实验名称：Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect ce... 来源：ChEMBL 靶标：Amine oxidase [flavin-containing] B External Id：CHEMBL4610239

实验名称：Inhibition of recombinant human MAO-B expressed in baculovirus infected BTI insect ce... 来源：ChEMBL 靶标：Amine oxidase [flavin-containing] B External Id：CHEMBL4610238

实验名称：Neuroprotective activity against H2O2-induced cytotoxicity in human SH-SY5Y cells ass... 来源：ChEMBL 靶标：SH-SY5Y External Id：CHEMBL4610241

实验名称：Neuroprotective activity against H2O2-induced cytotoxicity in human SH-SY5Y cells ass... 来源：ChEMBL 靶标：SH-SY5Y External Id：CHEMBL4610240

实验名称：Cytotoxicity against human SH-SY5Y cells assessed as effect on cell viability at 10 u... 来源：ChEMBL 靶标：SH-SY5Y External Id：CHEMBL4610243

实验名称：Mixed inhibition of recombinant human MAO-B expressed in baculovirus infected BTI ins... 来源：ChEMBL 靶标：Amine oxidase [flavin-containing] B External Id：CHEMBL4610246

实验名称：Tight-binding competitive inhibition of recombinant human MAO-B expressed in baculovi... 来源：ChEMBL 靶标：Amine oxidase [flavin-containing] B External Id：CHEMBL4610248

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