GLPG3970

Modify Date: 2024-01-03 21:32:42

GLPG3970 Structure
GLPG3970 structure
Common Name GLPG3970
CAS Number 2403733-82-2 Molecular Weight 504.50
Density N/A Boiling Point N/A
Molecular Formula C25H27F3N4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GLPG3970


GLPG3970 (compound 88) is a first-in-class SIK2/SIK3 inhibitor. GLPG3970 can be used for the research of inflammation and autoimmune disease[1].

 Names

Name GLPG3970

 GLPG3970 Biological Activity

Description GLPG3970 (compound 88) is a first-in-class SIK2/SIK3 inhibitor. GLPG3970 can be used for the research of inflammation and autoimmune disease[1].
Related Catalog
In Vivo GLPG3970 (10 mg/kg;口服,每日两次,连续五天) 在皮内注射 IL-23 诱导的银屑病表皮增生小鼠模型中降低耳厚[1]。 GLPG3970 (60 mg/kg;口服, 每日两次,直到老鼠被杀) 在小鼠胶原抗体诱导关节炎模型 (CAIA) 中,有良好的临床表现[1]。 GLPG3970 (10 mg/kg;口服, 每日两次,连续七天) 在小鼠 T 细胞转移模型中,与对照组相比降低疾病活动指数[1]。
References

[1]. DESROY N, et al. NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASES. WO/2019/238424. 2019.

 Chemical & Physical Properties

Molecular Formula C25H27F3N4O4
Molecular Weight 504.50
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